Investigating the Association between the Autophagy Markers LC3B,

DRAM LC3B SQSTM1/p62 autophagy autophagy-related genes (ATGs) high-grade gliomas (HGGs) low-grade gliomas (LGGs)

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
01 Jan 2024
Historique:
received: 27 11 2023
revised: 27 12 2023
accepted: 28 12 2023
medline: 11 1 2024
pubmed: 11 1 2024
entrez: 11 1 2024
Statut: epublish

Résumé

High-grade gliomas are extremely fatal tumors, marked by severe hypoxia and therapeutic resistance. Autophagy is a cellular degradative process that can be activated by hypoxia, ultimately resulting in tumor advancement and chemo-resistance. Our study aimed to examine the link between autophagy markers' expression in low-grade gliomas (LGGs) and high-grade gliomas (HGGs). In 39 glioma cases, we assessed the protein expression of autophagy markers LC3B,

Identifiants

pubmed: 38203743
pii: ijms25010572
doi: 10.3390/ijms25010572
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Farheen Danish (F)

Department of Pathology, Dow International Medical College, Dow University of Health Sciences, Karachi 75300, Pakistan.

Muhammad Asif Qureshi (MA)

Department of Pathology, Dow International Medical College, Dow University of Health Sciences, Karachi 75300, Pakistan.

Talat Mirza (T)

Departments of Research & Molecular Medicine, Ziauddin University, Karachi 75600, Pakistan.

Wajiha Amin (W)

Departments of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.

Sufiyan Sufiyan (S)

Departments of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.

Sana Naeem (S)

Departments of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.

Fatima Arshad (F)

Department of Pathology, Dow International Medical College, Dow University of Health Sciences, Karachi 75300, Pakistan.

Nouman Mughal (N)

Departments of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.

Classifications MeSH