Nuclear phosphoproteome reveals Prolyl Isomerase PIN1 as a modulator of oncogene-induced senescence.
Journal
Molecular & cellular proteomics : MCP
ISSN: 1535-9484
Titre abrégé: Mol Cell Proteomics
Pays: United States
ID NLM: 101125647
Informations de publication
Date de publication:
10 Jan 2024
10 Jan 2024
Historique:
received:
21
09
2023
revised:
05
12
2023
accepted:
08
01
2024
medline:
13
1
2024
pubmed:
13
1
2024
entrez:
12
1
2024
Statut:
aheadofprint
Résumé
Mammalian cells possess intrinsic mechanisms to prevent tumorigenesis upon deleterious mutations, including oncogene-induced senescence (OIS). The molecular mechanisms underlying OIS are, however, complex, and remain to be fully characterized. In this study, we analyzed the changes in the nuclear proteome and phosphoproteome of human lung fibroblast IMR90 cells during the progression of OIS induced by oncogenic RAS
Identifiants
pubmed: 38216124
pii: S1535-9476(24)00005-7
doi: 10.1016/j.mcpro.2024.100715
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
100715Informations de copyright
Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.