Heart Rate Variability as a Prognostic Tool for Gastroschisis Infants in the Neonatal Intensive Critical Unit.
Journal
American journal of perinatology
ISSN: 1098-8785
Titre abrégé: Am J Perinatol
Pays: United States
ID NLM: 8405212
Informations de publication
Date de publication:
12 Jan 2024
12 Jan 2024
Historique:
medline:
13
1
2024
pubmed:
13
1
2024
entrez:
12
1
2024
Statut:
aheadofprint
Résumé
Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics such as decreased variability occur due to the inflammatory response to sepsis in preterm infants. Test the hypothesis that infants with gastroschisis have decreased heart rate variability after birth and that this physiomarker may predict outcomes. We analyzed heart rate data from and clinical variables for all infants admitted with gastroschisis from 2009- 2020. 47 infants were admitted during the study period and had available data. Complex gastroschisis infants had reduced heart rate variability after birth. For those with sepsis and NEC, abnormal heart rate characteristics occurred early in the course of illness. Decreased HRV was associated with complex gastroschisis. Infants in this group experienced complications that prolonged time to full enteral feeding and time on TPN.
Sections du résumé
BACKGROUND
BACKGROUND
Gastroschisis is the most common congenital abdominal wall defect, with an increasing incidence. It results in extrusion of abdominal contents with associated delayed intestinal motility. Abnormal heart rate characteristics such as decreased variability occur due to the inflammatory response to sepsis in preterm infants.
OBJECTIVE
OBJECTIVE
Test the hypothesis that infants with gastroschisis have decreased heart rate variability after birth and that this physiomarker may predict outcomes.
STUDY DESIGN
METHODS
We analyzed heart rate data from and clinical variables for all infants admitted with gastroschisis from 2009- 2020.
RESULTS
RESULTS
47 infants were admitted during the study period and had available data. Complex gastroschisis infants had reduced heart rate variability after birth. For those with sepsis and NEC, abnormal heart rate characteristics occurred early in the course of illness.
CONCLUSION
CONCLUSIONS
Decreased HRV was associated with complex gastroschisis. Infants in this group experienced complications that prolonged time to full enteral feeding and time on TPN.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.