Dietary conjugated linoleic acid downregulates the AlCl
Adaptive response
Alzheimer's disease
Conjugated linoleic acid
Endoplasmic reticulum stress
Neuroprotection
Nuclear erythroid-related factor 2
Unfolded protein response
Journal
Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159
Informations de publication
Date de publication:
11 Jan 2024
11 Jan 2024
Historique:
received:
15
11
2023
revised:
23
12
2023
accepted:
04
01
2024
medline:
14
1
2024
pubmed:
14
1
2024
entrez:
13
1
2024
Statut:
aheadofprint
Résumé
Oxidative stress, hyperactivation of compensatory mechanisms (unfolded protein response, UPR; nuclear factor erythroid 2-related factor 2, Nrf2) and the stimulation of maladaptive response (inflammation/apoptosis) are interconnected pathogenic processes occurring during Alzheimer's disease (AD) progression. The neuroprotective ability of dietary Conjugated linoleic acid (CLAmix) in a mouse model of AlCl
Identifiants
pubmed: 38218550
pii: S0891-5849(24)00006-6
doi: 10.1016/j.freeradbiomed.2024.01.006
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare no conflict of interest.