High incidence of periodontitis in patients with ascitic decompensated cirrhosis.

Ascites Cirrhosis Decompensation Gingiva Periodontitis Survival

Journal

World journal of hepatology
ISSN: 1948-5182
Titre abrégé: World J Hepatol
Pays: United States
ID NLM: 101532469

Informations de publication

Date de publication:
27 Dec 2023
Historique:
received: 29 08 2023
revised: 27 09 2023
accepted: 06 12 2023
medline: 15 1 2024
pubmed: 15 1 2024
entrez: 15 1 2024
Statut: ppublish

Résumé

Periodontitis has been associated with various liver diseases. However, the relevance of periodontitis in the progression of decompensated cirrhosis remains inconclusive. In particular, it is unclear whether the common periodontitis pathogens, To investigate the significance of periodontitis, This prospective study was conducted at the University Hospital Hamburg-Eppendorf, a tertiary center in Northern Germany. A cohort of 27 patients with ascitic decompensated liver cirrhosis underwent dental examinations to assess the association between periodontitis and various clinical parameters of cirrhosis, as well as patient outcomes. PCR was used to test gingival samples, ascites, and stool for the presence of Periodontitis was diagnosed in 22 out of 27 (82%) ascite patients, which is significantly more common than in a control cohort of 100 unselected patients (59%, Decompensated cirrhotic patients frequently suffer from periodontitis. However, there was no evidence of the translocation of

Sections du résumé

BACKGROUND BACKGROUND
Periodontitis has been associated with various liver diseases. However, the relevance of periodontitis in the progression of decompensated cirrhosis remains inconclusive. In particular, it is unclear whether the common periodontitis pathogens,
AIM OBJECTIVE
To investigate the significance of periodontitis,
METHODS METHODS
This prospective study was conducted at the University Hospital Hamburg-Eppendorf, a tertiary center in Northern Germany. A cohort of 27 patients with ascitic decompensated liver cirrhosis underwent dental examinations to assess the association between periodontitis and various clinical parameters of cirrhosis, as well as patient outcomes. PCR was used to test gingival samples, ascites, and stool for the presence of
RESULTS RESULTS
Periodontitis was diagnosed in 22 out of 27 (82%) ascite patients, which is significantly more common than in a control cohort of 100 unselected patients (59%,
CONCLUSION CONCLUSIONS
Decompensated cirrhotic patients frequently suffer from periodontitis. However, there was no evidence of the translocation of

Identifiants

pubmed: 38223419
doi: 10.4254/wjh.v15.i12.1325
pmc: PMC10784813
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1325-1332

Informations de copyright

©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.

Auteurs

Sven Pischke (S)

First Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg 20246, Germany. spischke@uke.de.

Mohamad Motee Ashouri (MM)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.
Periodontics, Preventive and Restorative Dentistry, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Ulrike Peters (U)

Department of Periodontics, Preventive and Restorative Dentistry, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Anita Shiprov (A)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.
Periodontics, Preventive and Restorative Dentistry, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Julian Schulze Zur Wiesch (J)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Martina Sterneck (M)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Frank Fischer (F)

Department of Periodontics, Preventive and Restorative Dentistry, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Peter Huebener (P)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Maria Mader (M)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Lutz Fischer (L)

Department of Visceral Transplantation, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

Thorben Fründt (T)

First Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg 20246, Germany.

G Aarabi (G)

Department of Periodontics, Preventive and Restorative Dentistry, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Thomas Beikler (T)

Department of Periodontics, Preventive and Restorative Dentistry, University Medical Center Hamburg-Eppendorf, Hamburg 20246, Germany.

Classifications MeSH