Predictive models of epilepsy outcomes.


Journal

Current opinion in neurology
ISSN: 1473-6551
Titre abrégé: Curr Opin Neurol
Pays: England
ID NLM: 9319162

Informations de publication

Date de publication:
16 Jan 2024
Historique:
medline: 15 1 2024
pubmed: 15 1 2024
entrez: 15 1 2024
Statut: aheadofprint

Résumé

Multiple complex medical decisions are necessary in the course of a chronic disease like epilepsy. Predictive tools to assist physicians and patients in navigating this complexity have emerged as a necessity and are summarized in this review. Nomograms and online risk calculators are user-friendly and offer individualized predictions for outcomes ranging from safety of antiseizure medication withdrawal (accuracy 65-73%) to seizure-freedom, naming, mood, and language outcomes of resective epilepsy surgery (accuracy 72-81%). Improving their predictive performance is limited by the nomograms' inability to ingest complex data inputs. Conversely, machine learning offers the potential of multimodal and expansive model inputs achieving human-expert level accuracy in automated scalp electroencephalogram (EEG) interpretation but lagging in predictive performance or requiring validation for other applications. Good to excellent predictive models are now available to guide medical and surgical epilepsy decision-making with nomograms offering individualized predictions and user-friendly tools, and machine learning approaches offering the potential of improved performance. Future research is necessary to bridge the two approaches for optimal translation to clinical care.

Identifiants

pubmed: 38224138
doi: 10.1097/WCO.0000000000001241
pii: 00019052-990000000-00133
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

Références

Ryu J, Remembering Paul E. Meehl: historical contributions to predictive modeling in human behavior. Harv Rev Psychiatry 2023; 31:92–95.
Jehi L. Algorithms in clinical epilepsy practice: can they really help us predict epilepsy outcomes? Epilepsia 2020; 62:S71–S77.
Jehi L, Yardi R, Chagin K, et al. Development and validation of nomograms to provide individualised predictions of seizure outcomes after epilepsy surgery: a retrospective analysis. Lancet Neurol 2015; 14:283–290.
Fitzgerald Z, Morita-Sherman M, Hogue O, et al. Improving the prediction of epilepsy surgery outcomes using basic scalp EEG findings. Epilepsia 2021; 62:2439–2450.
Morita-Sherman M, Louis S, Vegh D, et al. Outcomes of resections that spare vs. remove an MRI-normal hippocampus. Epilepsia 2020; 61:2545–2557.
Busch RM, Hogue O, Kattan MW, et al. Nomograms to predict naming decline after temporal lobe surgery in adults with epilepsy. Neurology 2018; 91:e2144–e2152.
Doherty C, Nowacki AS, Pat McAndrews M, et al. Predicting mood decline following temporal lobe epilepsy surgery in adults. Epilepsia 2021; 62:450–459.
Busch RM, Hogue O, Miller M, et al. Nomograms to predict verbal memory decline after temporal lobe resection in adults with epilepsy. Neurology 2021; 97:e263–e274.
Stevelink R, Al-Toma D, Jansen FE, et al. Individualised prediction of drug resistance and seizure recurrence after medication withdrawal in people with juvenile myoclonic epilepsy: a systematic review and individual participant data meta-analysis. EClinicalMedicine 2022; 53:101732.
Lamberink HJ, Otte WM, Geerts AT, et al. Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis. Lancet Neurol 2017; 16:523–531.
Lamberink HJ, Boshuisen K, Otte WM, et al. Individualized prediction of seizure relapse and outcomes following antiepileptic drug withdrawal after pediatric epilepsy surgery. Epilepsia 2018; 59:e28–e33.
Ferreira-Atuesta C, de Tisi J, McEvoy AW, et al. Predictive models for starting antiseizure medication withdrawal following epilepsy surgery in adults. Brain 2023; 146:2389–2398.
Tveit J, Aurlien H, Plis S, et al. Automated interpretation of clinical electroencephalograms using artificial intelligence. JAMA Neurol 2023; 80:805–812.
Kural MA, Jing J, Fürbass F, et al. Accurate identification of EEG recordings with interictal epileptiform discharges using a hybrid approach: artificial intelligence supervised by human experts. Epilepsia 2022; 63:1064–1073.
Muhammad Usman S, Khalid S, Bashir S. A deep learning based ensemble learning method for epileptic seizure prediction. Comput Biol Med 2021; 136:104710.
Prathaban BP, Balasubramanian R. Dynamic learning framework for epileptic seizure prediction using sparsity based EEG Reconstruction with Optimized CNN classifier. Expert Syst Applic 2021; 170:114533.
Usman SM, Khalid S, Aslam MH. Epileptic seizures prediction using deep learning techniques. IEEE Access 2020; 8:39998–40007.
Alshebeili SA, Sedik A, Abd El-Rahiem B, et al. Inspection of EEG signals for efficient seizure prediction. Appl Acoust 2020; 166:107327.
Roy S, Kiral I, Mirmomeni M, et al. Evaluation of artificial intelligence systems for assisting neurologists with fast and accurate annotations of scalp electroencephalography data. EBioMedicine 2021; 66:103275.
Sinclair B, Cahill V, Seah J, et al. Machine learning approaches for imaging-based prognostication of the outcome of surgery for mesial temporal lobe epilepsy. Epilepsia 2022; 63:1081–1092.
Whiting AC, Morita-Sherman M, Li M, et al. Automated analysis of cortical volume loss predicts seizure outcomes after frontal lobectomy. Epilepsia 2021; 62:1074–1084.
Morita-Sherman M, Li M, Joseph B, et al. Incorporation of quantitative MRI in a model to predict temporal lobe epilepsy surgery outcome. Brain Commun 2021; 3:fcab164.
Feis D-L, Schoene-Bake J-C, Elger C, et al. Prediction of postsurgical seizure outcome in left mesial temporal lobe epilepsy. Neuroimage Clin 2013; 2:903–911.
Antony AR, Alexopoulos AV, González-Martínez JA, et al. Functional connectivity estimated from intracranial EEG predicts surgical outcome in intractable temporal lobe epilepsy. PLoS One 2013; 8:e77916.
Munsell BC, Wee C-Y, Keller SS, et al. Evaluation of machine learning algorithms for treatment outcome prediction in patients with epilepsy based on structural connectome data. Neuroimage 2015; 118:219–230.
Varatharajah Y, Joseph B, Brinkmann B, et al. Quantitative analysis of visually reviewed normal scalp EEG predicts seizure freedom following anterior temporal lobectomy. Epilepsia 2022; 63:1630–1642.
Hakeem H, Feng W, Chen Z, et al. Development and validation of a deep learning model for predicting treatment response in patients with newly diagnosed epilepsy. JAMA Neurol 2022; 79:986–996.
Zhao X, Jiang D, Hu Z, et al. Machine learning and statistic analysis to predict drug treatment outcome in pediatric epilepsy patients with tuberous sclerosis complex. Epilepsy Res 2022; 188:107040.
Wu J, Wang Y, Xiang L, et al. Machine learning model to predict the efficacy of antiseizure medications in patients with familial genetic generalized epilepsy. Epilepsy Res 2022; 181:106888.
An S, Malhotra K, Dilley C, et al. Predicting drug-resistant epilepsy—a machine learning approach based on administrative claims data. Epilepsy Behav 2018; 89:118–125.
Delen D, Davazdahemami B, Eryarsoy E, et al. Using predictive analytics to identify drug-resistant epilepsy patients. Health Informatics J 2020; 26:449–460.
Beheshti I, Sone D, Maikusa N, et al. Accurate lateralization and classification of MRI-negative 18F-FDG-PET-positive temporal lobe epilepsy using double inversion recovery and machine-learning. Comput Biol Med 2021; 137:104805.
Kang L, Chen J, Huang J, et al. Identifying epilepsy based on machine-learning technique with diffusion kurtosis tensor. CNS Neurosci Ther 2022; 28:354–363.
Gleichgerrcht E, Munsell BC, Alhusaini S, et al. Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study. Neuroimage Clin 2021; 31:102765.
Jehi L. Machine learning for precision epilepsy surgery. Epilepsy Curr 2023; 23:78–83.

Auteurs

Shehryar Sheikh (S)

Epilepsy Center, Neurological Institute.

Lara Jehi (L)

Epilepsy Center, Neurological Institute.
Center for Computational Life Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Classifications MeSH