Automated Prediction of Photographic Wound Assessment Tool in Chronic Wound Images.

Clinical decision support system Computer vision Image analysis PWAT Wound healing

Journal

Journal of medical systems
ISSN: 1573-689X
Titre abrégé: J Med Syst
Pays: United States
ID NLM: 7806056

Informations de publication

Date de publication:
16 Jan 2024
Historique:
received: 12 08 2023
accepted: 22 12 2023
medline: 16 1 2024
pubmed: 16 1 2024
entrez: 16 1 2024
Statut: epublish

Résumé

Many automated approaches have been proposed in literature to quantify clinically relevant wound features based on image processing analysis, aiming at removing human subjectivity and accelerate clinical practice. In this work we present a fully automated image processing pipeline leveraging deep learning and a large wound segmentation dataset to perform wound detection and following prediction of the Photographic Wound Assessment Tool (PWAT), automatizing the clinical judgement of the adequate wound healing. Starting from images acquired by smartphone cameras, a series of textural and morphological features are extracted from the wound areas, aiming to mimic the typical clinical considerations for wound assessment. The resulting extracted features can be easily interpreted by the clinician and allow a quantitative estimation of the PWAT scores. The features extracted from the region-of-interests detected by our pre-trained neural network model correctly predict the PWAT scale values with a Spearman's correlation coefficient of 0.85 on a set of unseen images. The obtained results agree with the current state-of-the-art and provide a benchmark for future artificial intelligence applications in this research field.

Identifiants

pubmed: 38227131
doi: 10.1007/s10916-023-02029-9
pii: 10.1007/s10916-023-02029-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

14

Informations de copyright

© 2024. The Author(s).

Références

Lindholm C, Searle R. Wound management for the 21st century: combining effectiveness and efficiency. Int Wound J. 2016;13(S2):5–15.
doi: 10.1111/iwj.12623 pubmed: 27460943 pmcid: 7949725
Olsson M, Järbrink K, Divakar U, Bajpai R, Upton Z, Schmidtchen A, et al. The humanistic and economic burden of chronic wounds: A systematic review. Wound Repair Regen Off Publ Wound Heal Soc Eur Tissue Repair Soc. gennaio 2019;27(1):114–25.
Stremitzer S, Wild T, Hoelzenbein T. How precise is the evaluation of chronic wounds by health care professionals? Int Wound J. giugno 2007;4(2):156–61.
doi: 10.1111/j.1742-481X.2007.00334.x
Sibbald RG, Elliott JA, Persaud-Jaimangal R, Goodman L, Armstrong DG, Harley C, et al. Wound Bed Preparation 2021. Adv Skin Wound Care. aprile 2021;34(4):183–95.
doi: 10.1097/01.ASW.0000733724.87630.d6
Haghpanah S, Bogie K, Wang X, Banks PG, Ho CH. Reliability of Electronic Versus Manual Wound Measurement Techniques. Arch Phys Med Rehabil. ottobre 2006;87(10):1396–402.
doi: 10.1016/j.apmr.2006.06.014
Bates-Jensen BM, McCreath HE, Harputlu D, Patlan A. Reliability of the Bates-Jensen wound assessment tool for pressure injury assessment: The pressure ulcer detection study. Wound Repair Regen Off Publ Wound Heal Soc Eur Tissue Repair Soc. luglio 2019;27(4):386–95.
Houghton PE, Kincaid CB, Campbell KE, Woodbury MG, Keast DH. Photographic assessment of the appearance of chronic pressure and leg ulcers. Ostomy Wound Manage. aprile 2000;46(4):20–6, 28–30.
Lustig M, Schwartz D, Bryant R, Gefen A. A machine learning algorithm for early detection of heel deep tissue injuries based on a daily history of sub-epidermal moisture measurements. Int Wound J. ottobre 2022;19(6):1339–48.
doi: 10.1111/iwj.13728
Wang C, Anisuzzaman DM, Williamson V, Dhar MK, Rostami B, Niezgoda J, et al. Fully automatic wound segmentation with deep convolutional neural networks. Sci Rep. 14 dicembre 2020;10(1):21897.
Scebba G, Zhang J, Catanzaro S, Mihai C, Distler O, Berli M, et al. Detect-and-segment: A deep learning approach to automate wound image segmentation. Inform Med Unlocked. 1 gennaio 2022;29:100884.
Wang C, Yan X, Smith M, Kochhar K, Rubin M, Warren SM, et al. A unified framework for automatic wound segmentation and analysis with deep convolutional neural networks. In: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). 2015. p. 2415–8.
Foltynski P, Ciechanowska A, Ladyzynski P. Wound surface area measurement methods. Biocybern Biomed Eng. 1 ottobre 2021;41(4):1454–65.
doi: 10.1016/j.bbe.2021.04.011
Chino DYT, Scabora LC, Cazzolato MT, Jorge AES, Traina-Jr C, Traina AJM. Segmenting skin ulcers and measuring the wound area using deep convolutional networks. Comput Methods Programs Biomed. luglio 2020;191:105376.
doi: 10.1016/j.cmpb.2020.105376
Ghazawi FM, Netchiporouk E, Rahme E, Tsang M, Moreau L, Glassman S, et al. Comprehensive analysis of cutaneous T-cell lymphoma (CTCL) incidence and mortality in Canada reveals changing trends and geographic clustering for this malignancy. Cancer. 15 settembre 2017;123(18):3550–67.
doi: 10.1002/cncr.30758 pubmed: 28493286
Liu Z, Agu E, Pedersen P, Lindsay C, Tulu B, Strong D. Chronic Wound Image Augmentation and Assessment Using Semi-Supervised Progressive Multi-Granularity EfficientNet. IEEE Open J Eng Med Biol. 2023;1–17.
Nguyen H, Agu E, Tulu B, Strong D, Mombini H, Pedersen P, et al. Machine learning models for synthesizing actionable care decisions on lower extremity wounds. Smart Health. 1 novembre 2020;18:100139.
doi: 10.1016/j.smhl.2020.100139 pubmed: 33299924
Mombini H, Tulu B, Strong D, Agu E, Nguyen H, Lindsay C, et al. Design of a Machine Learning System for Prediction of Chronic Wound Management Decisions. In: Hofmann S, Müller O, Rossi M, curatori. Designing for Digital Transformation Co-Creating Services with Citizens and Industry. Cham: Springer International Publishing; 2020. p. 15–27. (Lecture Notes in Computer Science).
Curti N, Merli Y, Zengarini C, Giampieri E, Merlotti A, Dall’Olio D, et al. Effectiveness of Semi-Supervised Active Learning in Automated Wound Image Segmentation. Int J Mol Sci. 2023; 24(1):706.
Amparo F, Wang H, Emami-Naeini P, Karimian P, Dana R. The Ocular Redness Index: A Novel Automated Method for Measuring Ocular Injection. Investig Opthalmology Vis Sci. 18 luglio 2013;54(7):4821.
doi: 10.1167/iovs.13-12217
Park IK, Chun YS, Kim KG, Yang HK, Hwang JM. New Clinical Grading Scales and Objective Measurement for Conjunctival Injection. Investig Opthalmology Vis Sci. 5 agosto 2013;54(8):5249.
doi: 10.1167/iovs.12-10678
Haralick RM, Shanmugam K, Dinstein I. Textural Features for Image Classification. IEEE Trans Syst Man Cybern. novembre 1973;SMC-3(6):610–21.
Anisuzzaman D m., Wang C, Rostami B, Gopalakrishnan S, Niezgoda J, Yu Z. Image-Based Artificial Intelligence in Wound Assessment: A Systematic Review. Adv Wound Care. dicembre 2022;11(12):687–709.
Curti N, Giampieri E, Guaraldi F, Bernabei F, Cercenelli L, Castellani G, et al. A Fully Automated Pipeline for a Robust Conjunctival Hyperemia Estimation. Appl Sci. 26 marzo 2021;11(7):2978.
doi: 10.3390/app11072978
Carlini G, Curti N, Strolin S, Giampieri E, Sala C, Dall’Olio D, et al. Prediction of Overall Survival in Cervical Cancer Patients Using PET/CT Radiomic Features. Appl Sci. 2022; 12(12):5946.
Filitto G, Coppola F, Curti N, Giampieri E, Dall’Olio D, Merlotti A, et al. Automated Prediction of the Response to Neoadjuvant Chemoradiotherapy in Patients Affected by Rectal Cancer. Cancers. 2022; 14(9):2231.
Lambin P, Leijenaar RTH, Deist TM, Peerlings J, de Jong EEC, van Timmeren J, et al. Radiomics: the bridge between medical imaging and personalized medicine. Nat Rev Clin Oncol. dicembre 2017;14(12):749–62.
doi: 10.1038/nrclinonc.2017.141
Wang Y, Herrington DM. Machine intelligence enabled radiomics. Nat Mach Intell. ottobre 2021;3(10):838–9.
doi: 10.1038/s42256-021-00404-0
Huang EP, O’Connor JPB, McShane LM, Giger ML, Lambin P, Kinahan PE, et al. Criteria for the translation of radiomics into clinically useful tests. Nat Rev Clin Oncol. febbraio 2023;20(2):69–82.
doi: 10.1038/s41571-022-00707-0 pubmed: 36443594
Hilt DE, Seegrist DW, United States. Forest Service., Northeastern Forest Experiment Station (Radnor Pa). Ridge, a computer program for calculating ridge regression estimates. Vol. no.236. Upper Darby, Pa: Dept. of Agriculture, Forest Service, Northeastern Forest Experiment Station; 1977.
Hu JY, Wang Y, Tong XM, Yang T. When to consider logistic LASSO regression in multivariate analysis? Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol. agosto 2021;47(8):2206.
Salvi M, Branciforti F, Veronese F, Zavattaro E, Tarantino V, Savoia P, et al. DermoCC-GAN: A new approach for standardizing dermatological images using generative adversarial networks. Comput Methods Programs Biomed. ottobre 2022;225:107040.
doi: 10.1016/j.cmpb.2022.107040
Barata C, Celebi ME, Marques JS. Improving dermoscopy image classification using color constancy. IEEE J Biomed Health Inform. maggio 2015;19(3):1146–52.

Auteurs

Nico Curti (N)

Department of Physics and Astronomy, University of Bologna, 40127, Bologna, Italy.
Data Science and Bioinformatics Laboratory, IRCCS Institute of Neurological Sciences of Bologna, 40139, Bologna, Italy.

Yuri Merli (Y)

Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Corrado Zengarini (C)

Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy. corrado.zengarini@studio.unibo.it.

Michela Starace (M)

Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Luca Rapparini (L)

Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Emanuela Marcelli (E)

Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.
eDIMESLab, Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Gianluca Carlini (G)

Data Science and Bioinformatics Laboratory, IRCCS Institute of Neurological Sciences of Bologna, 40139, Bologna, Italy.

Daniele Buschi (D)

Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Gastone C Castellani (GC)

Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Bianca Maria Piraccini (BM)

Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Tommaso Bianchi (T)

Native Medica s.r.l., Native Medica, 40138, Bologna, Italy.

Enrico Giampieri (E)

Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.

Classifications MeSH