Long-Term Oncological Control by Repeated Minimally Invasive Hepatectomy for Intrahepatic Cholangiocarcinoma Exhibiting Atypical Marker Expression of CK7-CK20+: A Case Report.

cytokeratin 20 cytokeratin 7 intrahepatic cholangiocarcinoma minimally invasive hepatectomy robotic liver resection

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Dec 2023
Historique:
accepted: 16 12 2023
medline: 17 1 2024
pubmed: 17 1 2024
entrez: 17 1 2024
Statut: epublish

Résumé

There are few reports of repeated liver resections being performed multiple times for intrahepatic recurrence of intrahepatic cholangiocarcinoma (ICC). We performed five minimally invasive liver resections and two minimally invasive lung resections for ICC with metachronous intrahepatic recurrence and lung metastases. Pathological examination revealed that all resected tumors were moderately differentiated mass-forming ICC with immunohistochemical marker expression of CK7 negative and CK20 positive. We present this as a rare case of ICC with atypical marker expression in which long-term tumor control was achieved with multiple minimally invasive liver resections over 47 months from the initial diagnosis.

Identifiants

pubmed: 38229809
doi: 10.7759/cureus.50639
pmc: PMC10789588
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e50639

Informations de copyright

Copyright © 2023, Harada et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Kei Harada (K)

Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.

Takahisa Fujikawa (T)

Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.

Yusuke Uemoto (Y)

Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.

Taisuke Matsuoka (T)

Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.

Classifications MeSH