Conditional deletion of
Atherosclerosis
CCL2
Inducible knockout
Inflammation
Smooth muscle cells
Journal
Atherosclerosis plus
ISSN: 2667-0895
Titre abrégé: Atheroscler Plus
Pays: Netherlands
ID NLM: 9918249514806676
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
received:
31
08
2023
revised:
29
11
2023
accepted:
18
12
2023
medline:
18
1
2024
pubmed:
18
1
2024
entrez:
18
1
2024
Statut:
epublish
Résumé
C-C motif chemokine ligand 2 (CCL2) is a pro-inflammatory chemokine important for monocyte recruitment to the arterial wall and atherosclerotic plaques. Global knockout of SMC-restricted Cre recombinase was activated at 6 weeks of age in mice with homozygous floxed or wildtype Unexpectedly, mice with SMC-specific SMC-specific deficiency of
Sections du résumé
Background and aims
UNASSIGNED
C-C motif chemokine ligand 2 (CCL2) is a pro-inflammatory chemokine important for monocyte recruitment to the arterial wall and atherosclerotic plaques. Global knockout of
Methods
UNASSIGNED
SMC-restricted Cre recombinase was activated at 6 weeks of age in mice with homozygous floxed or wildtype
Results
UNASSIGNED
Unexpectedly, mice with SMC-specific
Conclusions
UNASSIGNED
SMC-specific deficiency of
Identifiants
pubmed: 38234375
doi: 10.1016/j.athplu.2023.12.004
pii: S2667-0895(23)00051-2
pmc: PMC10792688
doi:
Types de publication
Journal Article
Langues
eng
Pagination
12-20Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.