Pannexin 1 Channels Control Cardiomyocyte Metabolism and Neutrophil Recruitment During Non-Ischemic Heart Failure.
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
30 Dec 2023
30 Dec 2023
Historique:
medline:
18
1
2024
pubmed:
18
1
2024
entrez:
18
1
2024
Statut:
epublish
Résumé
Pannexin 1 (PANX1), a ubiquitously expressed ATP release membrane channel, has been shown to play a role in inflammation, blood pressure regulation, and myocardial infarction. However, a possible role of PANX1 in cardiomyocytes in the progression of heart failure has not yet been investigated. We generated a novel mouse line with constitutive deletion of PANX1 in cardiomyocytes (Panx1
Identifiants
pubmed: 38234768
doi: 10.1101/2023.12.29.573679
pmc: PMC10793433
pii:
doi:
Types de publication
Preprint
Langues
eng