Angiopoietin 1 and integrin beta 1b are vital for zebrafish brain development.

GABA dopamine histamine hypothalamus neurogenesis neurovascular

Journal

Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935

Informations de publication

Date de publication:
2023
Historique:
received: 06 09 2023
accepted: 30 11 2023
medline: 18 1 2024
pubmed: 18 1 2024
entrez: 18 1 2024
Statut: epublish

Résumé

Angiopoietin 1 (angpt1) is essential for angiogenesis. However, its role in neurogenesis is largely undiscovered. This study aimed to identify the role of angpt1 in brain development, the mode of action of angpt1, and its prime targets in the zebrafish brain. We investigated the effects of embryonic brain angiogenesis and neural development using qPCR, We showed the co-localization of angpt1 with Our results prove that

Identifiants

pubmed: 38235293
doi: 10.3389/fncel.2023.1289794
pmc: PMC10792015
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1289794

Informations de copyright

Copyright © 2024 Chen, Martins, Marchica and Panula.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Yu-Chia Chen (YC)

Department of Anatomy, University of Helsinki, Helsinki, Finland.
Zebrafish Unit, Helsinki Institute of Life Science (HiLIFE), Helsinki, Finland.

Tomás A Martins (TA)

Department of Anatomy, University of Helsinki, Helsinki, Finland.
Zebrafish Unit, Helsinki Institute of Life Science (HiLIFE), Helsinki, Finland.

Valentina Marchica (V)

Department of Anatomy, University of Helsinki, Helsinki, Finland.
Zebrafish Unit, Helsinki Institute of Life Science (HiLIFE), Helsinki, Finland.

Pertti Panula (P)

Department of Anatomy, University of Helsinki, Helsinki, Finland.
Zebrafish Unit, Helsinki Institute of Life Science (HiLIFE), Helsinki, Finland.

Classifications MeSH