Bacterial flagella hijack type IV pili proteins to control motility.

flagellar motor mechanoresponse nanomachine

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
23 Jan 2024
Historique:
medline: 18 1 2024
pubmed: 18 1 2024
entrez: 18 1 2024
Statut: ppublish

Résumé

Bacterial flagella and type IV pili (TFP) are surface appendages that enable motility and mechanosensing through distinct mechanisms. These structures were previously thought to have no components in common. Here, we report that TFP and some flagella share proteins PilO, PilN, and PilM, which we identified as part of the

Identifiants

DOI: 10.1073/pnas.2317452121 PMID: 38236729
pubmed: 38236729
doi: 10.1073/pnas.2317452121
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2317452121

Subventions

Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : R01AI164682
Organisme : Department of Education and Training | Australian Research Council (ARC)
ID : DP210103056
Organisme : China Scholarship Council (CSC)
ID : 201904910692 to X.L
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : R01AI087846
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : R01AI132818
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : RO1AI116946

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Xiaolin Liu (X)

Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.
ORCID: 0000-0001-5891-4559

Shoichi Tachiyama (S)

Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT 06536.
Microbial Sciences Institute, Yale University, West Haven, CT 06516.
ORCID: 0000-0003-2010-212X

Xiaotian Zhou (X)

Infection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

Rommel A Mathias (RA)

Infection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.

Sharmin Q Bonny (SQ)

Infection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

Mohammad F Khan (MF)

Infection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
ORCID: 0000-0002-6373-7021

Yue Xin (Y)

Infection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.

Anna Roujeinikova (A)

Infection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.
ORCID: 0000-0001-8478-4751

Jun Liu (J)

Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT 06536.
Microbial Sciences Institute, Yale University, West Haven, CT 06516.
ORCID: 0000-0003-3108-6735

Karen M Ottemann (KM)

Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.
ORCID: 0000-0001-6265-7401

Classifications MeSH