Antioxidants for male infertility: therapeutic scheme and indications. A retrospective single-center real-life study.
Journal
Minerva endocrinology
ISSN: 2724-6116
Titre abrégé: Minerva Endocrinol (Torino)
Pays: Italy
ID NLM: 101777342
Informations de publication
Date de publication:
19 Jan 2024
19 Jan 2024
Historique:
medline:
19
1
2024
pubmed:
19
1
2024
entrez:
19
1
2024
Statut:
aheadofprint
Résumé
This single-center real-life study was conducted to evaluate the most effective combination of nutraceuticals and the most appropriate indications for the treatment of male infertile patients. Infertile patients aged 20-55 years were treated with a combination of antioxidants (Androlen Forty-three patients were enrolled. In the overall analysis, only progressive motility significantly improved after therapy. Subgroup analysis showed a significant increase in progressive motility, total motile sperm count (TMSC), and in the percentage of alive spermatozoa after treatment in the group A. Progressive motility improved significantly in patients with varicocele, while the TMSC in patients with varicocele and those with idiopathic infertility. The percentage of alive spermatozoa increased in patients with testicular hypotrophy. Treatment with antioxidants increased progressive sperm motility, especially in patients with varicocele or idiopathic infertility.
Sections du résumé
BACKGROUND
BACKGROUND
This single-center real-life study was conducted to evaluate the most effective combination of nutraceuticals and the most appropriate indications for the treatment of male infertile patients.
METHODS
METHODS
Infertile patients aged 20-55 years were treated with a combination of antioxidants (Androlen
RESULTS
RESULTS
Forty-three patients were enrolled. In the overall analysis, only progressive motility significantly improved after therapy. Subgroup analysis showed a significant increase in progressive motility, total motile sperm count (TMSC), and in the percentage of alive spermatozoa after treatment in the group A. Progressive motility improved significantly in patients with varicocele, while the TMSC in patients with varicocele and those with idiopathic infertility. The percentage of alive spermatozoa increased in patients with testicular hypotrophy.
CONCLUSIONS
CONCLUSIONS
Treatment with antioxidants increased progressive sperm motility, especially in patients with varicocele or idiopathic infertility.
Identifiants
pubmed: 38240682
pii: S2724-6507.23.04080-0
doi: 10.23736/S2724-6507.23.04080-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM