In vivo real-time positron emission particle tracking (PEPT) and single particle PET.


Journal

Nature nanotechnology
ISSN: 1748-3395
Titre abrégé: Nat Nanotechnol
Pays: England
ID NLM: 101283273

Informations de publication

Date de publication:
19 Jan 2024
Historique:
received: 16 05 2023
accepted: 30 11 2023
medline: 20 1 2024
pubmed: 20 1 2024
entrez: 19 1 2024
Statut: aheadofprint

Résumé

Positron emission particle tracking (PEPT) enables 3D localization and tracking of single positron-emitting radiolabelled particles with high spatiotemporal resolution. The translation of PEPT to the biomedical imaging field has been limited due to the lack of methods to radiolabel biocompatible particles with sufficient specific activity and protocols to isolate a single particle in the sub-micrometre size range, below the threshold for capillary embolization. Here we report two key developments: the synthesis and

Identifiants

pubmed: 38242986
doi: 10.1038/s41565-023-01589-8
pii: 10.1038/s41565-023-01589-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Juan Pellico (J)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Laurence Vass (L)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Amaia Carrascal-Miniño (A)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Francis Man (F)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Jana Kim (J)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Kavitha Sunassee (K)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

David Parker (D)

School of Physics and Astronomy, University of Birmingham, Birmingham, UK.

Philip J Blower (PJ)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Paul K Marsden (PK)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Rafael T M de Rosales (R)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. rafael.torres@kcl.ac.uk.

Classifications MeSH