Study of metalation of thioredoxin by gold(I) therapeutic compounds using combined liquid chromatography/capillary electrophoresis with inductively coupled plasma/electrospray MS/MS detection.

Au(I) complexes ESI–MS ICP-MS Metal-binding site Metal-protein adducts Trx

Journal

Analytical and bioanalytical chemistry
ISSN: 1618-2650
Titre abrégé: Anal Bioanal Chem
Pays: Germany
ID NLM: 101134327

Informations de publication

Date de publication:
20 Jan 2024
Historique:
received: 16 11 2023
accepted: 09 01 2024
revised: 22 12 2023
medline: 20 1 2024
pubmed: 20 1 2024
entrez: 20 1 2024
Statut: aheadofprint

Résumé

The reactivity of thioredoxin (Trx1) with the Au(I) drug auranofin (AF) and two therapeutic N-heterocyclic carbene (NHC)

Identifiants

DOI: 10.1007/s00216-024-05140-z PMID: 38244050
pubmed: 38244050
doi: 10.1007/s00216-024-05140-z
pii: 10.1007/s00216-024-05140-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

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Auteurs

Mikel Bernabeu De Maria (M)

Université de Pau Et Des Pays de L'Adour, E2S UPPA, CNRS, Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM-UMR 5254), 64053, Pau, France.

Magdalena Matczuk (M)

Faculty of Chemistry, Warsaw University of Technology, Noakowskiego St. 3, 00-664, Warsaw, Poland.

Diego Tesauro (D)

Department of Pharmacy and CIRPeB, Università degli Studi di Napoli Federico II, Via Montesano 49, 80131, Naples, Italy.

Michele Saviano (M)

Instituto Di Cristallografia (IC), CNR, 70126, Caserta, Italy.

Jacek Sikorski (J)

Faculty of Chemistry, Warsaw University of Technology, Noakowskiego St. 3, 00-664, Warsaw, Poland.

Giovanni Chiappetta (G)

Biological Mass Spectrometry and Proteomics (SMBP), ESPCI Paris, Université PSL, LPC CNRS UMR8249, 75005, Paris, France.

Simon Godin (S)

Université de Pau Et Des Pays de L'Adour, E2S UPPA, CNRS, Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM-UMR 5254), 64053, Pau, France.

Joanna Szpunar (J)

Université de Pau Et Des Pays de L'Adour, E2S UPPA, CNRS, Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM-UMR 5254), 64053, Pau, France.

Ryszard Lobinski (R)

Université de Pau Et Des Pays de L'Adour, E2S UPPA, CNRS, Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM-UMR 5254), 64053, Pau, France.
Faculty of Chemistry, Warsaw University of Technology, Noakowskiego St. 3, 00-664, Warsaw, Poland.

Luisa Ronga (L)

Université de Pau Et Des Pays de L'Adour, E2S UPPA, CNRS, Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM-UMR 5254), 64053, Pau, France. luisa.ronga@univ-pau.fr.

Classifications MeSH