Factors Affecting Quality of Life in Adolescents Living with Type 2 Diabetes: A Sub study of The Improving renal Complications in Adolescents with type 2 diabetes through REsearch cohort.
Adolescents
Quality of Life
Type 2 Diabetes
Journal
Canadian journal of diabetes
ISSN: 2352-3840
Titre abrégé: Can J Diabetes
Pays: Canada
ID NLM: 101148810
Informations de publication
Date de publication:
18 Jan 2024
18 Jan 2024
Historique:
received:
16
06
2023
revised:
26
10
2023
accepted:
10
01
2024
medline:
21
1
2024
pubmed:
21
1
2024
entrez:
20
1
2024
Statut:
aheadofprint
Résumé
Type 2 diabetes (T2D) impacts adolescents living in challenging socioeconomic conditions disproportionately. However, impacts of T2D on quality of life (QOL) in this context are unknown. The objective of this study was to evaluate QOL, and identify its biological, psychological, and social determinants amongst adolescents living with and without T2D from similar sociodemographic backgrounds. Relationships between glycemic stability, early complications and treatments of T2D and QOL were also examined. A total of 92 adolescents with T2D and 59 at-risk controls were included from the iCARE cohort. Main outcome was QOL (Pediatric QOL Inventory™ (PedsQL Mean total QOL scores among adolescents with T2D were lower than controls (67.0 ±14.8 vs 71.7 ± 16.2, p=0.04). Age, sex and % Indigenous ethnicity were not significantly different between groups. Mean duration of T2D was 2.3± 2.0 yrs. In multivariate analysis, QOL was not associated with diabetes status, but negative associations were seen between mental distress (β =-1.46, p<0.001) and food insecurity QOL (β =-6.26, p=0.037). No differences were seen between biological factors and QOL in either analysis. Significant factors associated with decreased QOL in adolescents living with T2D include mental distress and food insecurity, indicating areas for targeted intervention.
Sections du résumé
BACKGROUND
BACKGROUND
Type 2 diabetes (T2D) impacts adolescents living in challenging socioeconomic conditions disproportionately. However, impacts of T2D on quality of life (QOL) in this context are unknown. The objective of this study was to evaluate QOL, and identify its biological, psychological, and social determinants amongst adolescents living with and without T2D from similar sociodemographic backgrounds. Relationships between glycemic stability, early complications and treatments of T2D and QOL were also examined.
RESEARCH DESIGN AND METHODS
METHODS
A total of 92 adolescents with T2D and 59 at-risk controls were included from the iCARE cohort. Main outcome was QOL (Pediatric QOL Inventory™ (PedsQL
RESULTS
RESULTS
Mean total QOL scores among adolescents with T2D were lower than controls (67.0 ±14.8 vs 71.7 ± 16.2, p=0.04). Age, sex and % Indigenous ethnicity were not significantly different between groups. Mean duration of T2D was 2.3± 2.0 yrs. In multivariate analysis, QOL was not associated with diabetes status, but negative associations were seen between mental distress (β =-1.46, p<0.001) and food insecurity QOL (β =-6.26, p=0.037). No differences were seen between biological factors and QOL in either analysis.
CONCLUSIONS
CONCLUSIONS
Significant factors associated with decreased QOL in adolescents living with T2D include mental distress and food insecurity, indicating areas for targeted intervention.
Identifiants
pubmed: 38244988
pii: S1499-2671(24)00014-5
doi: 10.1016/j.jcjd.2024.01.004
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.