ATP13A2 (PARK9) and basal ganglia function.

Kufor-Rakeb Syndrome Parkinson’s disease alpha-synuclein iron manganese mitochondria neuronal ceroid lipofuscinosis zinc

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2023
Historique:
received: 05 07 2023
accepted: 11 12 2023
medline: 22 1 2024
pubmed: 22 1 2024
entrez: 22 1 2024
Statut: epublish

Résumé

ATP13A2 is a lysosomal protein involved in polyamine transport with loss of function mutations associated with multiple neurodegenerative conditions. These include early onset Parkinson's disease, Kufor-Rakeb Syndrome, neuronal ceroid lipofuscinosis, hereditary spastic paraplegia, and amyotrophic lateral sclerosis. While

Identifiants

pubmed: 38249738
doi: 10.3389/fneur.2023.1252400
pmc: PMC10796451
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1252400

Informations de copyright

Copyright © 2024 Croucher and Fleming.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Kristina M Croucher (KM)

Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States.
Biomedical Sciences Graduate Program, Kent State University, Kent, OH, United States.

Sheila M Fleming (SM)

Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States.

Classifications MeSH