Therapeutic Effects of IL-1RA against Acute Bacterial Infections, including Antibiotic-Resistant Strains.
IL-1
IL-1 receptor antagonist
acute cystitis
acute pyelonephritis
antibiotic resistance
immunotherapy
infection
substance P
urinary tract infection
uropathogenic Escherichia coli
Journal
Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317
Informations de publication
Date de publication:
31 Dec 2023
31 Dec 2023
Historique:
received:
07
12
2023
revised:
25
12
2023
accepted:
28
12
2023
medline:
22
1
2024
pubmed:
22
1
2024
entrez:
22
1
2024
Statut:
epublish
Résumé
Innate immunity is essential for the anti-microbial defense, but excessive immune activation may cause severe disease. In this study, immunotherapy was shown to prevent excessive innate immune activation and restore the anti-bacterial defense.
Identifiants
pubmed: 38251349
pii: pathogens13010042
doi: 10.3390/pathogens13010042
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : the European Union's Horizon 2020 research and innovation program
ID : No. 954360