Rheb1 is required for limb growth through regulating chondrogenesis in growth plate.
Chondrocyte Proliferation
Chondrocyte maturation
Chondrogenesis
Rheb1
mTORC1
Journal
Cell and tissue research
ISSN: 1432-0878
Titre abrégé: Cell Tissue Res
Pays: Germany
ID NLM: 0417625
Informations de publication
Date de publication:
23 Jan 2024
23 Jan 2024
Historique:
received:
29
11
2022
accepted:
04
01
2024
medline:
23
1
2024
pubmed:
23
1
2024
entrez:
22
1
2024
Statut:
aheadofprint
Résumé
Ras homology enriched in the brain (Rheb) is well established as a critical regulator of cell proliferation and differentiation in response to growth factors and nutrients. However, the role of Rheb1 in limb development remains unknown. Here, we found that Rheb1 was dynamically expressed during the proliferation and differentiation of chondrocytes in the growth plate. Given that Prrx1
Identifiants
pubmed: 38253890
doi: 10.1007/s00441-024-03861-2
pii: 10.1007/s00441-024-03861-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Natural Science Foundation of China
ID : 81871745
Informations de copyright
© 2024. The Author(s).
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