Stress-Induced Immunosuppression Inhibits Regional Immune Responses in Chicken Adipose Tissue Partially through Suppressing T Cells by Up-Regulating Steroid Metabolism.

adipose tissue chicken immune response lipid metabolism stress-induced immunosuppression

Journal

Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614

Informations de publication

Date de publication:
10 Jan 2024
Historique:
received: 21 11 2023
revised: 31 12 2023
accepted: 08 01 2024
medline: 23 1 2024
pubmed: 23 1 2024
entrez: 23 1 2024
Statut: epublish

Résumé

Lipid metabolism plays an important role in maintaining lipid homeostasis and regulating immune functions. However, the regulations and mechanisms of lipid metabolism on the regional immune function of avian adipose tissue (AT) have not been reported. In this study, qRT-PCR was used to investigate the changes and relationships of different lipid metabolism pathways in chicken AT during stress-induced immunosuppression (SIIS) inhibiting immune response to Newcastle disease virus vaccine, then the miRNA regulation patterns of 3-hydroxy-3-methylglutaryl-CoA reductase (

Identifiants

pubmed: 38254394
pii: ani14020225
doi: 10.3390/ani14020225
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Natural Science Foundation of Heilongjiang Province
ID : no. LH2019C073

Auteurs

Wei Zhang (W)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Xinxin Xu (X)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Rui Zhang (R)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Yufei Tian (Y)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Xiaoli Ma (X)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Xiangnan Wang (X)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Yi Jiang (Y)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Chaolai Man (C)

College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.

Classifications MeSH