National Multicenter Study on the Comparison of Robotic and Open Thymectomy for Thymic Neoplasms in Myasthenic Patients: Surgical, Neurological and Oncological Outcomes.

mediastinal surgery myasthenia gravis robotic surgery sternotomy thymectomy thymic neoplasm

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
18 Jan 2024
Historique:
received: 29 12 2023
revised: 16 01 2024
accepted: 16 01 2024
medline: 23 1 2024
pubmed: 23 1 2024
entrez: 23 1 2024
Statut: epublish

Résumé

Thymectomy is the gold standard in the treatment of thymic neoplasm and plays a key role in the therapeutic path of myasthenia gravis. For years, sternotomy has been the traditional approach for removing anterior mediastinal lesions, although the robotic thymectomy is now widely performed. The literature is still lacking in papers comparing the two approaches and evaluating long-term oncological and neurological outcomes. This study aims to analyze the postoperative results of open and robotic thymectomy for thymic neoplasms in myasthenic patients. Surgical, oncological and neurological data of myasthenic patients affected by thymic neoplasms and surgically treated with extended thymectomy, both with the open and the robotic approach, in six Italian Thoracic Centers between 2011 and 2021 were evaluated. A total of 213 patients were enrolled in the study: 110 (51.6%) were treated with the open approach, and 103 (48.4%) were treated with robotic surgery. The open surgery, compared with the robotic, presented a shorter operating time (

Identifiants

pubmed: 38254894
pii: cancers16020406
doi: 10.3390/cancers16020406
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Elisa Sicolo (E)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Carmelina Cristina Zirafa (CC)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Gaetano Romano (G)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Jury Brandolini (J)

Department of Thoracic Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.

Angela De Palma (A)

Unit of Thoracic Surgery, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", 70121 Bari, Italy.

Stefano Bongiolatti (S)

Thoracic Surgery Unit, Department of Experimental and Clinical Medicine, Careggi University Hospital, 50134 Florence, Italy.

Filippo Tommaso Gallina (FT)

Thoracic Surgery Unit IRCCS Regina Elena National Cancer Center, 00144 Rome, Italy.

Sara Ricciardi (S)

Unit of Thoracic Surgery, Azienda Ospedaliera San Camillo Forlanini, 00152 Rome, Italy.

Michelangelo Maestri (M)

Neurology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Melania Guida (M)

Neurology Unit, Department of Clinical and Experimental Medicine, University Hospital of Pisa, 56124 Pisa, Italy.

Riccardo Morganti (R)

Section of Statistics, University Hospital of Pisa, 56124 Pisa, Italy.

Graziana Carleo (G)

Unit of Thoracic Surgery, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", 70121 Bari, Italy.

Giovanni Mugnaini (G)

Thoracic Surgery Unit, Department of Experimental and Clinical Medicine, Careggi University Hospital, 50134 Florence, Italy.

Riccardo Tajè (R)

Thoracic Surgery Unit IRCCS Regina Elena National Cancer Center, 00144 Rome, Italy.

Fabrizia Calabró (F)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Alessandra Lenzini (A)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Federico Davini (F)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Giuseppe Cardillo (G)

Unit of Thoracic Surgery, Azienda Ospedaliera San Camillo Forlanini, 00152 Rome, Italy.

Francesco Facciolo (F)

Thoracic Surgery Unit IRCCS Regina Elena National Cancer Center, 00144 Rome, Italy.

Luca Voltolini (L)

Thoracic Surgery Unit, Department of Experimental and Clinical Medicine, Careggi University Hospital, 50134 Florence, Italy.

Giuseppe Marulli (G)

Unit of Thoracic Surgery, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", 70121 Bari, Italy.

Piergiorgio Solli (P)

Department of Thoracic Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.

Franca Melfi (F)

Minimally Invasive and Robotic Thoracic Surgery-Surgical, Medical, Molecular and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy.

Classifications MeSH