Association of Glutamine and Glutamate Metabolism with Mortality among Patients at Nutritional Risk-A Secondary Analysis of the Randomized Clinical Trial EFFORT.

biomarker glutamate glutamine individualized nutrition support malnutrition polymorbid patient

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
10 Jan 2024
Historique:
received: 07 12 2023
revised: 02 01 2024
accepted: 09 01 2024
medline: 23 1 2024
pubmed: 23 1 2024
entrez: 23 1 2024
Statut: epublish

Résumé

Glutamine and its metabolite glutamate serve as the main energy substrates for immune cells, and their plasma levels drop during severe illness. Therefore, glutamine supplementation in the critical care setting has been advocated. However, little is known about glutamine metabolism in severely but not critically ill medical patients. We investigated the prognostic impact of glutamine metabolism in a secondary analysis of the

Identifiants

pubmed: 38257115
pii: nu16020222
doi: 10.3390/nu16020222
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Swiss National Science Foundation
ID : PP00P3_150531
Pays : Switzerland
Organisme : Swiss National Science Foundation
ID : PP00P3_176972
Pays : Switzerland

Auteurs

Carla Wunderle (C)

Division of General Internal and Emergency Medicine, University Department of Medicine, Kantonsspital Aarau, Tellstrasse 25, 5001 Aarau, Switzerland.

Diana von Arx (D)

Medical Faculty, University of Basel, 4056 Basel, Switzerland.

Sydney Chiara Mueller (SC)

Medical Faculty, University of Basel, 4056 Basel, Switzerland.
Faculty of Biomedical Scienes, Università della Svizzera italiana (USI), 6900 Lugano, Switzerland.

Luca Bernasconi (L)

Institute of Laboratory Medicine, Kantonsspital Aarau, Tellstrasse 25, 5001 Aarau, Switzerland.

Peter Neyer (P)

Institute of Laboratory Medicine, Kantonsspital Aarau, Tellstrasse 25, 5001 Aarau, Switzerland.

Pascal Tribolet (P)

Division of General Internal and Emergency Medicine, University Department of Medicine, Kantonsspital Aarau, Tellstrasse 25, 5001 Aarau, Switzerland.
Department of Health Professions, Bern University of Applied Sciences, Murtenstrasse 10, 3008 Bern, Switzerland.
Faculty of Life Sciences, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.

Zeno Stanga (Z)

Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism (UDEM), Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, 3010 Bern, Switzerland.

Beat Mueller (B)

Division of General Internal and Emergency Medicine, University Department of Medicine, Kantonsspital Aarau, Tellstrasse 25, 5001 Aarau, Switzerland.
Faculty of Biomedical Scienes, Università della Svizzera italiana (USI), 6900 Lugano, Switzerland.

Philipp Schuetz (P)

Division of General Internal and Emergency Medicine, University Department of Medicine, Kantonsspital Aarau, Tellstrasse 25, 5001 Aarau, Switzerland.
Medical Faculty, University of Basel, 4056 Basel, Switzerland.

Classifications MeSH