Functional and Radiologic Outcomes of Degenerative Versus Traumatic Full-Thickness Rotator Cuff Tears Involving the Supraspinatus Tendon.

degenerative rotator cuff tear rotator cuff repair shoulder arthroscopy shoulder surgery outcome traumatic rotator cuff tear

Journal

The American journal of sports medicine
ISSN: 1552-3365
Titre abrégé: Am J Sports Med
Pays: United States
ID NLM: 7609541

Informations de publication

Date de publication:
23 Jan 2024
Historique:
medline: 23 1 2024
pubmed: 23 1 2024
entrez: 23 1 2024
Statut: aheadofprint

Résumé

Arthroscopic rotator cuff repair (ARCR) is among the most commonly performed orthopaedic procedures. Several factors-including age, sex, and tear severity-have been identified as predictors for outcome after repair. The influence of the tear etiology on functional and structural outcome remains controversial. To investigate the influence of tear etiology (degenerative vs traumatic) on functional and structural outcomes in patients with supraspinatus tendon tears. Cohort study; Level of evidence, 2. Patients undergoing ARCR from 19 centers were prospectively enrolled between June 2020 and November 2021. Full-thickness, nonmassive tears involving the supraspinatus tendon were included. Tears were classified as degenerative (chronic shoulder pain, no history of trauma) or traumatic (acute, traumatic onset, no previous shoulder pain). Range of motion, strength, the Subjective Shoulder Value, the Oxford Shoulder Score (OSS), and the Constant-Murley Score (CMS) were assessed before (baseline) and 6 and 12 months after ARCR. The Subjective Shoulder Value and the OSS were also determined at the 24-month follow-up. Repair integrity after 12 months was documented, as well as additional surgeries up to the 24-month follow-up. Tear groups were compared using mixed models adjusted for potential confounding effects. From a cohort of 973 consecutive patients, 421 patients (degenerative tear, n = 230; traumatic tear, n = 191) met the inclusion criteria. The traumatic tear group had lower mean baseline OSS and CMS scores but significantly greater score changes 12 months after ARCR (OSS, 18 [SD, 8]; CMS, 34 [SD,18] vs degenerative: OSS, 15 [SD, 8]; CMS, 22 [SD, 15]) ( Patients with degenerative and traumatic full-thickness supraspinatus tendon tears who had ARCR show satisfactory short-term functional results. Although patients with traumatic tears have lower baseline functional scores, they rehabilitate over time and show comparable clinical results 1 year after ARCR. Similarly, degenerative and traumatic rotator cuff tears show comparable structural outcomes, which suggests that degenerated tendons retain healing potential.

Sections du résumé

BACKGROUND UNASSIGNED
Arthroscopic rotator cuff repair (ARCR) is among the most commonly performed orthopaedic procedures. Several factors-including age, sex, and tear severity-have been identified as predictors for outcome after repair. The influence of the tear etiology on functional and structural outcome remains controversial.
PURPOSE UNASSIGNED
To investigate the influence of tear etiology (degenerative vs traumatic) on functional and structural outcomes in patients with supraspinatus tendon tears.
STUDY DESIGN UNASSIGNED
Cohort study; Level of evidence, 2.
METHODS UNASSIGNED
Patients undergoing ARCR from 19 centers were prospectively enrolled between June 2020 and November 2021. Full-thickness, nonmassive tears involving the supraspinatus tendon were included. Tears were classified as degenerative (chronic shoulder pain, no history of trauma) or traumatic (acute, traumatic onset, no previous shoulder pain). Range of motion, strength, the Subjective Shoulder Value, the Oxford Shoulder Score (OSS), and the Constant-Murley Score (CMS) were assessed before (baseline) and 6 and 12 months after ARCR. The Subjective Shoulder Value and the OSS were also determined at the 24-month follow-up. Repair integrity after 12 months was documented, as well as additional surgeries up to the 24-month follow-up. Tear groups were compared using mixed models adjusted for potential confounding effects.
RESULTS UNASSIGNED
From a cohort of 973 consecutive patients, 421 patients (degenerative tear, n = 230; traumatic tear, n = 191) met the inclusion criteria. The traumatic tear group had lower mean baseline OSS and CMS scores but significantly greater score changes 12 months after ARCR (OSS, 18 [SD, 8]; CMS, 34 [SD,18] vs degenerative: OSS, 15 [SD, 8]; CMS, 22 [SD, 15]) (
CONCLUSION UNASSIGNED
Patients with degenerative and traumatic full-thickness supraspinatus tendon tears who had ARCR show satisfactory short-term functional results. Although patients with traumatic tears have lower baseline functional scores, they rehabilitate over time and show comparable clinical results 1 year after ARCR. Similarly, degenerative and traumatic rotator cuff tears show comparable structural outcomes, which suggests that degenerated tendons retain healing potential.

Identifiants

pubmed: 38259113
doi: 10.1177/03635465231219253
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3635465231219253

Déclaration de conflit d'intérêts

One or more of the authors has declared the following potential conflict of interest or source of funding: This project was funded by the Swiss National Science Foundation (SNF Project ID 320030_184959, http://p3.snf.ch/project-184959). Complementary grants were provided by Swiss Orthopedics to support project site documentation. The following sites are funding their participation in the project: Charitè Medicine University, Berlin, Germany; Public Hospital Solothurn, Solothurn, Switzerland; Endoclinic, Zurich, Switzerland; Inselspital, Bern, Switzerland; and University Clinic Balgrist, Zurich, Switzerland. C.B. received funding for her research salary from the University Hospital Basel, Department of Surgery. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto.

Auteurs

Cornelia Baum (C)

Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Laurent Audigé (L)

Surgical Outcome Research Center, Department of Clinical Research, University Hospital of Basel, Basel, Switzerland; Research and Development, Shoulder and Elbow Surgery, Schulthess Klinik, Zurich, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Thomas Stojanov (T)

Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland; Research and Development, Shoulder and Elbow Surgery, Schulthess Klinik, Zurich, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sebastian A Müller (SA)

Department of Orthopaedic and Trauma Surgery, Shoulder and Elbow, Cantonal Hospital Baselland, Bruderholz, Switzerland; Faculty of Medicine, University of Basel, Basel, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christian Candrian (C)

Trauma and Ortho Unit, Ospedale Regionale di Lugano, Lugano, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Andreas M Müller (AM)

Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Claudio Rosso (C)

Principal Investigator [PI]).
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Lena Fankhauser (L)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Gernot Willscheid (G)

Charitè Medicine University, Berlin, DE.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Philipp Moroder (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Doruk Akgün (D)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Victor Danzinger (V)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Henry Gebauer (H)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jan-Philipp Imiolczyk (JP)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Katrin Karpinski (K)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Lucca Lacheta (L)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Marvin Minkus (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Alp Paksoy (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Eduardo Samaniego (E)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Kathi Thiele (K)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Isabella Weiss (I)

Cantonal Hospital Baselland, Bruderholz, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Thomas Suter (T)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Julia Müller-Lebschi (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sebastian Mueller (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Markus Saner (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Claudia Haag-Schumacher (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Giorgio Tamborrini-Schütz (G)

Public Hospital Solothurn, Solothurn, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Mai Lan Dao Trong (MLD)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Carlos Buitrago-Tellez (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Julian Hasler (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Ulf Riede (U)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sandra Weber (S)

Hôpital du Valais-Centre Hospitalier du Valais Romand, Martigny, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Beat Moor (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Matthias Biner (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sarah Fournier (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Nicolas Gallusser (N)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Deborah Marietan (D)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sebastien Pawlak (S)

Endoclinic, Zurich, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christoph Spormann (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Britta Hansen (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Nadja Mamisch (N)

Klinik Gut, St Moritz, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Holger Durchholz (H)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jakob Bräm (J)

Hirslanden Clinique la Colline, Geneva, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Gregory Cunningham (G)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Abed Kourhani (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sarah Ossipow (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Patricia Simao (P)

La Tour Hospital, Meyrin, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Alexandre Lädermann (A)

Inselspital, Bern, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Rainer Egli (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Stephanie Erdbrink (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Remy Flückiger (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Paolo Lombardo (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Tawan Pinworasarn (T)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Philipp Scacchi (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Johannes Weihs (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Matthias Zumstein (M)

In-Motion, Wallisellen, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Matthias Flury (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Ralph Berther (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christine Ehrmann (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Larissa Hübscher (L)

Institute of Social and Preventive Medicine, University of Bern, Bern, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

David Schwappach (D)

Cantonal Hospital of Baden, Baden, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Karim Eid (K)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Susanne Bensler (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Yannick Fritz (Y)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Nisha Grünberger (N)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Philipp Kriechling (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Daniel Langthaler (D)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Richard Niehaus (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Raffaela Nobs (R)

Cantonal Hospital of Winterthur, Winterthur, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Emanuel Benninger (E)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Quintin de Groot (Q)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Aleksis Doert (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sebastian Ebert (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Philemon Grimm (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Fabian Mottier (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Markus Pisan (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jan Schätz (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Ariane Schwank (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Julian Wiedenbach (J)

Schulthess Klinik, Zurich, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Markus Scheibel (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Laurent Audigé (L)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Frederik Bellmann (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Daniela Brune (D)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Marije de Jong (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Stefan Diermayr (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

David Endell (D)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Marco Etter (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Florian Freislederer (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Nikitas Gkikopoulos (N)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Michael Glanzmann (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Cécile Grobet (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christian Jung (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Fabrizio Moro (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Philipp Moroder (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Ralph Ringer (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jan Schätz (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Hans-Kaspar Schwyzer (HK)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Béatrice Weber (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Martina Wehrli (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Barbara Wirth (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Manuela Nötzli (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Anne Franz (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jörg Oswald (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Birgit Steiger (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Yacine Ameziane (Y)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christopher Child (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Giovanni Spagna (G)

Ospedale Regionale di Lugano, Lugano, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christian Candrian (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Filippo Del Grande (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Pietro Feltri (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Giuseppe Filardo (G)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Francesco Marbach (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Florian Schönweger (F)

Cantonal Hospital of St. Gallen, St. Gallen, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Bernhard Jost (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Michael Badulescu (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Stephanie Lüscher (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Fabian Napieralski (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Lena Öhrström (L)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Martin Olach (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jan Rechsteiner (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Jörg Scheler (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christian Spross (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Vilijam Zdravkovic (V)

Orthopädie Sonnenhof, Bern, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Matthias A Zumstein (MA)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Adrian Chlasta (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Kate Gerber (K)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Annabel Hayoz (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Julia Müller-Lebschi (J)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Frederick Schuster (F)

University Clinic Balgrist, Zurich, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Karl Wieser (K)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Paul Borbas (P)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Samy Bouaicha (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Roland Camenzind (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sabrina Catanzaro (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christian Gerber (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Florian Grubhofer (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Anita Hasler (A)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Bettina Hochreiter (B)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Roy Marcus (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Farah Selman (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Reto Sutter (R)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sabine Wyss (S)

University Library Basel, University of Basel, Basel, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Christian Appenzeller-Herzog (C)

University Hospital of Basel, Basel, CH.
Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Soheila Aghlmandi (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Ilona Ahlborn (I)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Cornelia Baum (C)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Franziska Eckers (F)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Kushtrim Grezda (K)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Simone Hatz (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Sabina Hunziker (S)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Thomas Stojanov (T)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Mohy Taha (M)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Giorgio Tamborrini-Schütz (G)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Andreas Marc Mueller (AM)

Investigation performed at University Hospital Basel, Basel and the Schulthess Klinik, Zurich, Switzerland.

Classifications MeSH