Astrocytes in fragile X syndrome.
astrocytes
autism spectrum disorder
calcium signaling
cell differentiation
cholesterol
fragile X syndrome
glutamate
induced pluripotent stem cells
Journal
Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935
Informations de publication
Date de publication:
2023
2023
Historique:
received:
16
10
2023
accepted:
11
12
2023
medline:
23
1
2024
pubmed:
23
1
2024
entrez:
23
1
2024
Statut:
epublish
Résumé
Astrocytes have an important role in neuronal maturation and synapse function in the brain. The interplay between astrocytes and neurons is found to be altered in many neurodevelopmental disorders, including fragile X syndrome (FXS) that is the most common inherited cause of intellectual disability and autism spectrum disorder. Transcriptional, functional, and metabolic alterations in
Identifiants
pubmed: 38259499
doi: 10.3389/fncel.2023.1322541
pmc: PMC10800791
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1322541Informations de copyright
Copyright © 2024 Talvio and Castrén.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.