Hospitalization-based epidemiology of systemic and cardiac amyloidosis in the Veneto Region, Italy.

Cardiac amyloidosis Epidemiology Hospitalizations Incidence Prevalence Systemic amyloidosis

Journal

International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291

Informations de publication

Date de publication:
21 Jan 2024
Historique:
received: 03 10 2023
revised: 27 12 2023
accepted: 18 01 2024
medline: 24 1 2024
pubmed: 24 1 2024
entrez: 23 1 2024
Statut: aheadofprint

Résumé

Defining the epidemiology of systemic and cardiac amyloidosis (CA) is a contemporary challenge. The present study aimed to estimate incidence and time trends in amyloidosis-related hospitalizations (AH) in Veneto Region (5 million inhabitants, Northeastern Italy). International Classification of Diseases (ICD-9) codes were used to identify AH in Veneto from 2010 to 2020. AH were defined as any hospitalization with a discharge summary reporting an ICD-9 code for systemic amyloidosis. Hospitalization for CA was defined as records with ICD-9 code for systemic amyloidosis and ICD-9 code for heart failure,cardiomyopathy or arrhythmia. Hospital/outpatient encounters for carpal tunnel syndrome (CTS) surgeries also were extracted. AH incidence was estimated using a buffer of 5 years. In the time range 2015-2020, the incidence rate of AH was 23.5 cases per 10 In Veneto, we recorded a significantly increasing trend in the incidence of AH, with concordant increasing prevalence estimates. Tailored screening of selected patients with previous multiple CTS surgeries may be reasonable.

Identifiants

DOI: 10.1016/j.ijcard.2024.131804 PMID: 38262481
pubmed: 38262481
pii: S0167-5273(24)00169-4
doi: 10.1016/j.ijcard.2024.131804
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

131804

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest Dr. De Michieli received honoraria from Pfizer Inc., Alnylam Pharmaceuticals, AstraZeneca Spa.Dr. Cipriani received honoraria from Pfizer Inc., Alnylam Pharmaceuticals, AstraZeneca Spa. The other Authors have nothing to disclose.

Auteurs

Laura De Michieli (L)

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.

Giorgia Stoppa (G)

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy; Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.

Giulio Sinigiani (G)

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.

Lorenzo Previato (L)

Internal Medicine Unit, University Hospital of Padua, Italy.

Giulia Lorenzoni (G)

Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.

Alessandro Salvalaggio (A)

Padova Neuroscience Center (PNC), University of Padua, Italy; Department of Neurosciences, University of Padua, Italy.

Tamara Berno (T)

Ematology Unit, University Hospital of Padua, Italy.

Martina Perazzolo Marra (MP)

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy; Cardiology Unit, University Hospital of Padua, Italy.

Chiara Briani (C)

Department of Neurosciences, University of Padua, Italy.

Sabino Iliceto (S)

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy; Cardiology Unit, University Hospital of Padua, Italy.

Annibale Biggeri (A)

Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.

Dolores Catelan (D)

Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy.

Alberto Cipriani (A)

Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy; Cardiology Unit, University Hospital of Padua, Italy. Electronic address: alberto.cipriani@unipd.it.

Classifications MeSH