Functional activation of pyruvate dehydrogenase in human brain using hyperpolarized [1-
bicarbonate
brain activation
dissolution dynamic nuclear polarization
fMRS
hyperpolarized pyruvate
pyruvate dehydrogenase
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
May 2024
May 2024
Historique:
revised:
28
12
2023
received:
03
06
2023
accepted:
29
12
2023
pubmed:
24
1
2024
medline:
24
1
2024
entrez:
24
1
2024
Statut:
ppublish
Résumé
Pyruvate, produced from either glucose, glycogen, or lactate, is the dominant precursor of cerebral oxidative metabolism. Pyruvate dehydrogenase (PDH) flux is a direct measure of cerebral mitochondrial function and metabolism. Detection of [ From seven sedentary adults in good general health, time-resolved [ In the course of visual stimulation, the measured [ We demonstrated the utility of
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1822-1833Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK127984
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB015908
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS107409
Pays : United States
Organisme : ODCDC CDC HHS
ID : S10 OD018468
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR029119
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK127984
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB015908
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS107409
Pays : United States
Organisme : ODCDC CDC HHS
ID : S10 OD018468
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR029119
Pays : United States
Informations de copyright
© 2024 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.
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