Variations in neonatal mortality of preterm infants with intraparenchymal haemorrhage in Europe: the EPICE cohort.

Epidemiology Mortality Neonatology Palliative Care

Journal

Archives of disease in childhood. Fetal and neonatal edition
ISSN: 1468-2052
Titre abrégé: Arch Dis Child Fetal Neonatal Ed
Pays: England
ID NLM: 9501297

Informations de publication

Date de publication:
25 Jan 2024
Historique:
received: 02 07 2023
accepted: 14 01 2024
medline: 26 1 2024
pubmed: 26 1 2024
entrez: 25 1 2024
Statut: aheadofprint

Résumé

The aim of this study was to investigate variations in mortality before neonatal intensive care unit (NICU) discharge of infants born preterm with intraparenchymal haemorrhage (IPH) in Europe with a special interest for withdrawing life-sustaining therapy (WLST). Secondary analysis of the Effective Perinatal Intensive Care in Europe (EPICE) cohort, 2011-2012. Nineteen regions in 11 European countries. All infants born between 24 Mortality rate with multivariable analysis after adjustment for GA, antenatal steroids and gender. WLST policies were described among NICUs and within countries. Among 6828 infants born alive between 24 In infants with IPH, rates of death before discharge and death after WLST varied between European countries. These variations in mortality impede studying reliable outcomes in infants with IPH across European countries and encourage reflection of clinical practices of WLST across European units.

Identifiants

pubmed: 38272659
pii: archdischild-2023-326038
doi: 10.1136/archdischild-2023-326038
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Investigateurs

J Lebeer (J)
P Van Reempts (P)
E Bruneel (E)
E Cloet (E)
A Oostra (A)
E Ortibus (E)
I Sarrechia (I)
K Boerch (K)
L Huusom (L)
P Pedersen (P)
T Weber (T)
L Toome (L)
H Varendi (H)
M Ma Nnamaa (M)
P Y Ancel (PY)
A Burguet (A)
P H Jarreau (PH)
V Pierrat (V)
P Truffert (P)
R F Maier (RF)
H Ehrhardt (H)
M Zemlin (M)
B Misselwitz (B)
S Schmidt (S)
L Wohlers (L)
M Cuttini (M)
D Di Lallo (D)
G Ancora (G)
D Baronciani (D)
V Carnielli (V)
I Croci (I)
G Faldella (G)
F Ferrari (F)
F Franco (F)
G Gargano (G)
A van Heijst (A)
C Koopman-Esseboom (C)
J Gadzinowski (J)
J Mazela (J)
A Montgomery (A)
T Pikuła (T)
H Barros (H)
R Costa (R)
LMendes Grac A (LG)
M do Machado (M)
C Rodrigues (C)
T Rodrigues (T)
U Aden (U)
A K Edstedt Bonamy (AK)
M Norman (M)
E S Draper (ES)
E M Boyle (EM)
A Fenton (A)
S J Johnson (SJ)
B N Manktelow (BN)
Dwa Milligan (D)
S Mader (S)
N Thiele (N)
J M Walz (JM)
S Petrou (S)
J Zeitlin (J)
A M Aubert (AM)
M Bonet (M)
C Bonnet (C)
R El Raffei (R)
A Piedvache (A)
A V Seppanen (AV)

Informations de copyright

© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Charline Loth (C)

University Grenoble Alpes, Neonatology Department, CHU Grenoble-Alpes, Grenoble, France.

Ludovic Treluyer (L)

Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, F-75004 Paris, France.

Véronique Pierrat (V)

Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, F-75004 Paris, France.

Anne Ego (A)

Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, F-75004 Paris, France.
Grenoble Alpes, Inserm CIC1406, CHU Grenoble, Grenoble, France.

Adrien M Aubert (AM)

Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, F-75004 Paris, France.

Thierry Debillon (T)

University Grenoble Alpes, Neonatology Department, CHU Grenoble-Alpes, Grenoble, France.
University Grenoble Alpes, CNRS, Public Health Department CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France.

Jennifer Zeitlin (J)

Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, F-75004 Paris, France.

Heloise Torchin (H)

Université Paris Cité, Inserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Obstetrical Perinatal and Pediatric Epidemiology Research Team, EPOPé, F-75004 Paris, France.
Neonatal Intensive Care Unit, Port-Royal Maternity, Paris, Île-de-France, France.

Marie Chevallier (M)

University Grenoble Alpes, Neonatology Department, CHU Grenoble-Alpes, Grenoble, France MChevallier3@chu-grenoble.fr.
University Grenoble Alpes, CNRS, Public Health Department CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France.

Classifications MeSH