Renal Function After CT-Guided Cryoablation of Small Renal Tumours in Patients with Solitary Kidney: An Analysis of European Multinational Prospective EuRECA Registry.

Cryoablation Image-guided Renal cell carcinoma Renal function Renal masses Solitary kidney

Journal

Cardiovascular and interventional radiology
ISSN: 1432-086X
Titre abrégé: Cardiovasc Intervent Radiol
Pays: United States
ID NLM: 8003538

Informations de publication

Date de publication:
25 Jan 2024
Historique:
received: 08 05 2023
accepted: 22 11 2023
medline: 26 1 2024
pubmed: 26 1 2024
entrez: 25 1 2024
Statut: aheadofprint

Résumé

Treatment of renal cell carcinoma (RCC) in patients with solitary kidneys remains challenging. The purpose of this multicentre cohort study was to explore how renal function is affected by percutaneous image-guided cryoablation in patients with solitary kidneys. Data from the European Registry for Renal Cryoablation database were extracted on patients with RCC in solitary kidneys treated with image-guided, percutaneous cryoablation. Patients were excluded if they had multiple tumours, had received previous treatment of the tumour, or were treated with more than one cryoablation procedure. Pre- and post-treatment eGFR (within 3 months of the procedure) were compared. Of 222 patients with solitary kidneys entered into the database, a total of 70 patients met inclusion criteria. The mean baseline eGFR was 55.8 ± 16.8 mL/min/1.73 m Image-guided renal cryoablation appears to be safe and effective for renal function preservation in patients with RCC in a solitary kidney. Following cryoablation, all patients had preservation of renal function without the need for dialysis or progression in chronic kidney disease stage despite the statistically significant reduction in eGFR. LEVEL OF EVIDENCE 3: Observational study.

Identifiants

pubmed: 38273129
doi: 10.1007/s00270-023-03634-4
pii: 10.1007/s00270-023-03634-4
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Pia I Pietersen (PI)

Department of Radiology, Odense University Hospital, Kløvervænget 37, 5000, Odense, Denmark.
UNIFY - Research and Innovation Unit of Radiology, University of Southern Denmark, Odense, Denmark.

Sarah Stougaard (S)

Department of Radiology, Odense University Hospital, Kløvervænget 37, 5000, Odense, Denmark.
UNIFY - Research and Innovation Unit of Radiology, University of Southern Denmark, Odense, Denmark.

Francis X Keeley (FX)

Bristol Urological Institute, North Bristol NHS Trust, Bristol, UK.

Brunolf Lagerveld (B)

Department of Urology, OLVG, Amsterdam, The Netherlands.

David Breen (D)

Department of Radiology, Southampton University Hospitals, Southampton, UK.

Alexander King (A)

Department of Radiology, Southampton University Hospitals, Southampton, UK.

Tommy K Nielsen (TK)

Department of Urology, Aarhus University Hospital, Aarhus, Denmark.

Marco van Strijen (M)

Department of Radiology, St Antonius Hospital, Nieuwegein, The Netherlands.

Julien Garnon (J)

Department of Interventional Radiology, Nouvel Hôpital Civil, 67096, Strasbourg cedex, France.

Des Alcorn (D)

Department of Interventional Radiology, Gartnavel General Hospital, Glasgow, UK.

Eric de Kerviler (E)

Radiology Department, Saint-Louis Hospital, AP-HP, 1, Avenue Claude-Vellefaux, 75475, Paris cedex 10, France.

Patricia Zondervan (P)

Department of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Tze M Wah (TM)

Department of Diagnostic and Interventional Radiology, Institute of Oncology, Leeds Teaching Hospitals Trust, St. James's University Hospital, Leeds, UK.

Theresa Junker (T)

Department of Radiology, Odense University Hospital, Kløvervænget 37, 5000, Odense, Denmark.
UNIFY - Research and Innovation Unit of Radiology, University of Southern Denmark, Odense, Denmark.

Ole Graumann (O)

Department of Radiology, Odense University Hospital, Kløvervænget 37, 5000, Odense, Denmark. olegraumann@dadlnet.dk.
UNIFY - Research and Innovation Unit of Radiology, University of Southern Denmark, Odense, Denmark. olegraumann@dadlnet.dk.

Classifications MeSH