Neuropathic Pain Affects Quality of Life in Breast Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy.
Journal
Pain management nursing : official journal of the American Society of Pain Management Nurses
ISSN: 1532-8635
Titre abrégé: Pain Manag Nurs
Pays: United States
ID NLM: 100890606
Informations de publication
Date de publication:
25 Jan 2024
25 Jan 2024
Historique:
received:
25
03
2023
revised:
30
12
2023
accepted:
30
12
2023
medline:
27
1
2024
pubmed:
27
1
2024
entrez:
26
1
2024
Statut:
aheadofprint
Résumé
Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter. This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy. A cross-sectional, correlational design. This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan. One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled. Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast. The study indicated that improving depression (B = -10.87, p < .001) and neuropathic pain (B = -8.33, p = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors. This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.
Sections du résumé
BACKGROUND
BACKGROUND
Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter.
AIMS
OBJECTIVE
This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy.
DESIGN
METHODS
A cross-sectional, correlational design.
SETTINGS
METHODS
This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan.
PARTICIPANTS/SUBJECTS
METHODS
One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled.
METHODS
METHODS
Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast.
RESULTS
RESULTS
The study indicated that improving depression (B = -10.87, p < .001) and neuropathic pain (B = -8.33, p = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors.
CONCLUSIONS
CONCLUSIONS
This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.
Identifiants
pubmed: 38278750
pii: S1524-9042(23)00250-3
doi: 10.1016/j.pmn.2023.12.013
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest All authors declare no conflicts of interest.