Defining an Optimized Workflow for Enriching and Analyzing Residual Tumor Populations Using Intracellular Markers.
Journal
The Journal of molecular diagnostics : JMD
ISSN: 1943-7811
Titre abrégé: J Mol Diagn
Pays: United States
ID NLM: 100893612
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
received:
23
06
2023
revised:
12
12
2023
accepted:
11
01
2024
pubmed:
28
1
2024
medline:
28
1
2024
entrez:
27
1
2024
Statut:
ppublish
Résumé
Tumor relapse is well recognized to arise from treatment-resistant residual populations. Strategies enriching such populations for in-depth downstream analyses focus on tumor-specific surface markers; however, enrichment using intracellular biomarkers remains challenging. Using B-cell lymphoma as an exemplar, we demonstrate feasibility to enrich B-cell lymphoma 2 (BCL2)
Identifiants
pubmed: 38280422
pii: S1525-1578(24)00008-4
doi: 10.1016/j.jmoldx.2024.01.003
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
245-256Subventions
Organisme : Cancer Research UK
ID : 26819
Pays : United Kingdom
Informations de copyright
Copyright © 2024 Association for Molecular Pathology and American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.