Toxigenic Endophyte-Infected Tall Fescue and Ergot Alkaloids.

Agalactia Dysgalactia Dystocia Ergopeptine alkaloids Ergot Ergot alkaloids Ergotism Fescue toxicosis

Journal

The Veterinary clinics of North America. Equine practice
ISSN: 1558-4224
Titre abrégé: Vet Clin North Am Equine Pract
Pays: United States
ID NLM: 8511904

Informations de publication

Date de publication:
27 Jan 2024
Historique:
medline: 29 1 2024
pubmed: 29 1 2024
entrez: 28 1 2024
Statut: aheadofprint

Résumé

"Fescue toxicosis" and reproductive ergotism present identical toxidromes in late-gestational mares and, likely, other equids. Both toxic syndromes are caused by ergopeptine alkaloids (EPAs) of fungal origin, and they are collectively referred to as equine ergopeptine alkaloid toxicosis (EEPAT). EPAs are produced by either a toxigenic endophyte (Epichloë coenophiala) in tall fescue and/or a nonendophytic fungus (Claviceps purpurea), infecting small grains and grasses. EEPAT can cause hypoprolactinemia-induced agalactia/dysgalactia, prolonged gestation, dystocia, and other reproductive abnormalities in mares, as well as failure of passive transfer in their frequently dysmature/overmature/postmature foals. Prevention relies on eliminating exposures and/or reversing hypoprolactinemia.

Identifiants

pubmed: 38281896
pii: S0749-0739(24)00001-4
doi: 10.1016/j.cveq.2024.01.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure No disclosure.

Auteurs

Tim J Evans (TJ)

Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri-Columbia, W226 Veterinary Medicine Building, 1520 Rollins Street, Columbia, MO 65211, USA. Electronic address: evanst@missouri.edu.

Megan C Romano (MC)

Department of Veterinary Science, Martin-Gatton College of Agriculture, Food, and Environment, University of Kentucky Veterinary Diagnostic Laboratory, University of Kentucky, 1490 Bull Lea Road, PO Box 14125, Lexington, KY 40512-4125, USA.

Classifications MeSH