A theragenerative bio-nanocomposite consisting of black phosphorus quantum dots for bone cancer therapy and regeneration.

Bioactive glass Black phosphorus Bone cancer therapy Microwave treatment Tissue regeneration

Journal

Bioactive materials
ISSN: 2452-199X
Titre abrégé: Bioact Mater
Pays: China
ID NLM: 101685294

Informations de publication

Date de publication:
May 2024
Historique:
received: 03 12 2023
revised: 11 01 2024
accepted: 18 01 2024
medline: 29 1 2024
pubmed: 29 1 2024
entrez: 29 1 2024
Statut: epublish

Résumé

Recently, the term theragenerative has been proposed for biomaterials capable of inducing therapeutic approaches followed by repairing/regenerating the tissue/organ. This study is focused on the design of a new theragenerative nanocomposite composed of an amphiphilic non-ionic surfactant (Pluronic F127), bioactive glass (BG), and black phosphorus (BP). The nanocomposite was prepared through a two-step synthetic strategy, including a microwave treatment that turned BP nanosheets (BPNS) into quantum dots (BPQDs) with 5 ± 2 nm dimensions

Identifiants

DOI: 10.1016/j.bioactmat.2024.01.018 PMID: 38283385 PMC: PMC10818087
pubmed: 38283385
doi: 10.1016/j.bioactmat.2024.01.018
pii: S2452-199X(24)00028-8
pmc: PMC10818087
doi:

Types de publication

Journal Article

Langues

eng

Pagination

99-121

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors have declared that there is no conflict of interest.

Auteurs

Ashkan Bigham (A)

Institute of Polymers, Composites and Biomaterials, National Research Council of Italy (IPCB-CNR), Viale John Fitzgerald Kennedy 54, Mostra d'Oltremare Padiglione 20, 80125, Naples, Italy.
Department of Chemical, Materials and Production Engineering, University of Naples Federico II, Piazzale V. Tecchio 80, 80125, Naples, Italy.

Ines Fasolino (I)

Institute of Polymers, Composites and Biomaterials, National Research Council of Italy (IPCB-CNR), Viale John Fitzgerald Kennedy 54, Mostra d'Oltremare Padiglione 20, 80125, Naples, Italy.

Silvia Borsacchi (S)

Institute for the Chemistry of OrganoMetallic Compounds-ICCOM, Italian National Research Council-CNR, via G. Moruzzi 1, 56124, Pisa, Italy.
Center for Instrument Sharing of the University of Pisa (CISUP), 56126, Pisa, Italy.

Carmen Valente (C)

Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via Pietro Castellino 111, 80131, Napoli, Italy.

Lucia Calucci (L)

Institute for the Chemistry of OrganoMetallic Compounds-ICCOM, Italian National Research Council-CNR, via G. Moruzzi 1, 56124, Pisa, Italy.
Center for Instrument Sharing of the University of Pisa (CISUP), 56126, Pisa, Italy.

Gabriele Turacchio (G)

Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via Pietro Castellino 111, 80131, Napoli, Italy.

Marianna Pannico (M)

Institute of Polymers, Composites, and Biomaterials, National Research Council of Italy (IPCB-CNR), Pozzuoli, Italy.

Manuel Serrano-Ruiz (M)

Institute for the Chemistry of OrganoMetallic Compounds-ICCOM, National Research Council-CNR, Sesto Fiorentino, Italy.

Luigi Ambrosio (L)

Institute of Polymers, Composites and Biomaterials, National Research Council of Italy (IPCB-CNR), Viale John Fitzgerald Kennedy 54, Mostra d'Oltremare Padiglione 20, 80125, Naples, Italy.

Maria Grazia Raucci (MG)

Institute of Polymers, Composites and Biomaterials, National Research Council of Italy (IPCB-CNR), Viale John Fitzgerald Kennedy 54, Mostra d'Oltremare Padiglione 20, 80125, Naples, Italy.

Classifications MeSH