The RAVI registry: prospective, multicenter study of radial access in embolization procedures - 30 days follow up.


Journal

CVIR endovascular
ISSN: 2520-8934
Titre abrégé: CVIR Endovasc
Pays: Switzerland
ID NLM: 101738484

Informations de publication

Date de publication:
30 Jan 2024
Historique:
received: 06 11 2023
accepted: 05 12 2023
medline: 30 1 2024
pubmed: 30 1 2024
entrez: 30 1 2024
Statut: epublish

Résumé

There is a lack of registry studies about transradial access (TRA) outcomes. This prospective registry evaluated the TRA and procedure outcomes of visceral embolizations performed via TRA with 30-day follow-up. Prospective, multicenter registry included uterine fibroids (UFE), prostate artery (PAE), liver tumors (LT), and other hypervascular tumors (OHT) embolization performed in six US hospitals. Between February 2020 and January 2022, 99 patients underwent one radial artery visceral intervention (RAVI); 70 had UFE (70.7%), 16 PAE (16.2%), 7 LT (7.1%), and 6 OHT (6.1%). The mean age was 50.1 (±11.1) years, and 74/99 (74.7%) were females. The primary safety endpoints included hand ischemia, stroke, and death. Procedural success was defined as completing the intended procedure via radial artery (RA) access. Technical success was defined as the successful delivery of HydroPearl™ microspheres and complete embolization of the target vessel. Procedural and technical successes were 100% and 97%, respectively. There was no stroke, hand ischemia, radial-to-femoral conversion, access-related serious adverse events, or clinically evident radial artery occlusion at 30 days. There were two deaths: one respiratory failure and one progression of liver disease. Minor RA-related adverse event included arterial spasm, hematoma, and post-procedure discomfort. This prospective, multicenter, open-label registry confirmed the high safety profile and effectiveness of radial access in UFE, PAE, LT, and OHT embolization procedures without stroke, hand ischemia, or access-related serious adverse events at 30-day follow-up.

Sections du résumé

BACKGROUND BACKGROUND
There is a lack of registry studies about transradial access (TRA) outcomes. This prospective registry evaluated the TRA and procedure outcomes of visceral embolizations performed via TRA with 30-day follow-up.
MATERIAL & METHODS METHODS
Prospective, multicenter registry included uterine fibroids (UFE), prostate artery (PAE), liver tumors (LT), and other hypervascular tumors (OHT) embolization performed in six US hospitals. Between February 2020 and January 2022, 99 patients underwent one radial artery visceral intervention (RAVI); 70 had UFE (70.7%), 16 PAE (16.2%), 7 LT (7.1%), and 6 OHT (6.1%). The mean age was 50.1 (±11.1) years, and 74/99 (74.7%) were females. The primary safety endpoints included hand ischemia, stroke, and death. Procedural success was defined as completing the intended procedure via radial artery (RA) access. Technical success was defined as the successful delivery of HydroPearl™ microspheres and complete embolization of the target vessel.
RESULTS RESULTS
Procedural and technical successes were 100% and 97%, respectively. There was no stroke, hand ischemia, radial-to-femoral conversion, access-related serious adverse events, or clinically evident radial artery occlusion at 30 days. There were two deaths: one respiratory failure and one progression of liver disease. Minor RA-related adverse event included arterial spasm, hematoma, and post-procedure discomfort.
CONCLUSION CONCLUSIONS
This prospective, multicenter, open-label registry confirmed the high safety profile and effectiveness of radial access in UFE, PAE, LT, and OHT embolization procedures without stroke, hand ischemia, or access-related serious adverse events at 30-day follow-up.

Identifiants

pubmed: 38289433
doi: 10.1186/s42155-023-00415-5
pii: 10.1186/s42155-023-00415-5
doi:

Types de publication

Journal Article

Langues

eng

Pagination

15

Subventions

Organisme : Terumo BCT
ID : TIS2019-02
Organisme : Terumo BCT
ID : TIS2019-02
Organisme : Terumo BCT
ID : TIS2019-02
Organisme : Terumo BCT
ID : TIS2019-02
Organisme : Terumo BCT
ID : TIS2019-02
Organisme : Terumo BCT
ID : TIS2019-02

Investigateurs

Andre Uflacker (A)
Ricardo Yamada (R)
Kirubahara Vaheesan (K)
Ali Abdullah Malik (AA)
Afsheen Sherwani (A)
Clayton Commander (C)
Maureen Kohi (M)
Robert Lookstein (R)
Francis Nowakowski (F)
Rahul Patel (R)
Rajesh Patel (R)
Joseph Titano (J)
Mona Ranade (M)

Informations de copyright

© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

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Auteurs

Marcelo Guimaraes (M)

Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive MSC 226, Room 3304, Charleston, SC, 29425, USA. guimarae@musc.edu.

Aaron Fischman (A)

Department of Diagnostic, Molecular and Interventional Radiology, Urology and Surgery, Icahn School of Medicine, Mt. Sinai Hospital, New York City, NY, USA.

Hyeon Yu (H)

Department of Radiology, Division of Interventional Radiology, University of North Carolina, Chapel Hill, NC, USA.

Jordan Tasse (J)

Department of Diagnostic Radiology and Nuclear Medicine, Division of Interventional Radiology, Rush University Medical College, Chicago, IL, USA.

Jessica Stewart (J)

Department of Radiology, Division of Interventional Radiology, University of North Carolina, Chapel Hill, NC, USA.
Department of Radiology, Division of Interventional Radiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Keith Pereira (K)

Division of Interventional Radiology, St. Louis University School of Medicine, St. Louis, MO, USA.

Classifications MeSH