Feasibility of the J-PET to monitor the range of therapeutic proton beams.

J-PET Monte Carlo simulations PET Proton radiotherapy Range monitoring

Journal

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888

Informations de publication

Date de publication:
29 Jan 2024
Historique:
received: 29 05 2023
revised: 15 01 2024
accepted: 23 01 2024
medline: 30 1 2024
pubmed: 30 1 2024
entrez: 30 1 2024
Statut: aheadofprint

Résumé

The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J-PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread-Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J-PET scanner prototype dedicated to the proton beam range assessment. The investigations indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10

Identifiants

DOI: 10.1016/j.ejmp.2024.103301 PMID: 38290179
pubmed: 38290179
pii: S1120-1797(24)00095-4
doi: 10.1016/j.ejmp.2024.103301
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

103301

Informations de copyright

Copyright © 2024 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The Authors declare no conflict of interest.

Auteurs

Jakub Baran (J)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland. Electronic address: jakubbaran92@gmail.com.

Damian Borys (D)

Silesian University of Technology, Department of Systems Biology and Engineering, Gliwice, Poland; Biotechnology Centre, Silesian University of Technology, Gliwice, Poland; Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland.

Karol Brzeziński (K)

Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland; Instituto de Física Corpuscular (IFIC), CSIC-UV, Valencia, Spain.

Jan Gajewski (J)

Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland.

Michał Silarski (M)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Neha Chug (N)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Aurélien Coussat (A)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Eryk Czerwiński (E)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Meysam Dadgar (M)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Kamil Dulski (K)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Kavya V Eliyan (KV)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Aleksander Gajos (A)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Krzysztof Kacprzak (K)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Łukasz Kapłon (Ł)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Konrad Klimaszewski (K)

Department of Complex Systems, National Centre for Nuclear Research, Otwock-Świerk, Poland.

Paweł Konieczka (P)

Department of Complex Systems, National Centre for Nuclear Research, Otwock-Świerk, Poland.

Renata Kopeć (R)

Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland.

Grzegorz Korcyl (G)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Tomasz Kozik (T)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Wojciech Krzemień (W)

High Energy Physics Division, National Centre for Nuclear Research, Otwock-Świerk, Poland.

Deepak Kumar (D)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Antony J Lomax (AJ)

Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland; Physics Department, ETH Zürich, Zürich, Switzerland.

Keegan McNamara (K)

Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland; Physics Department, ETH Zürich, Zürich, Switzerland.

Szymon Niedźwiecki (S)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Paweł Olko (P)

Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland.

Dominik Panek (D)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Szymon Parzych (S)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Elena Perez Del Rio (E)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Lech Raczyński (L)

Department of Complex Systems, National Centre for Nuclear Research, Otwock-Świerk, Poland.

Moyo Simbarashe (M)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Sushil Sharma (S)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.
Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Roman Y Shopa (RY)

Department of Complex Systems, National Centre for Nuclear Research, Otwock-Świerk, Poland.

Tomasz Skóra (T)

National Oncology Institute, National Research Institute, Krakow Branch, Krakow, Poland.

Magdalena Skurzok (M)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Paulina Stasica (P)

Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland.

Ewa Ł Stępień (EŁ)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Keyvan Tayefi (K)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Faranak Tayefi (F)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Damien C Weber (DC)

Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department of Radiation Oncology, University Hospital of Zürich, Zürich Switzerland; Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland.

Carla Winterhalter (C)

Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland; Physics Department, ETH Zürich, Zürich, Switzerland.

Wojciech Wiślicki (W)

Department of Complex Systems, National Centre for Nuclear Research, Otwock-Świerk, Poland.

Paweł Moskal (P)

Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, 11 Łojasiewicza St 30-348 Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, 30-348 Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland.

Antoni Ruciński (A)

Institute of Nuclear Physics Polish Academy of Sciences, 31-342, Kraków, Poland.

Classifications MeSH