[Obstetrical outcome of renal transplant patients followed in a type III maternity hospital. Retrospective study from 2000 to 2020].
Devenir obstétrical des patientes transplantées rénales suivies dans une maternité de type III. Étude rétrospective de 2000 à 2020.
maternal and fœtal complications
pregnancy
renal function
renal transplantation
Journal
Gynecologie, obstetrique, fertilite & senologie
ISSN: 2468-7189
Titre abrégé: Gynecol Obstet Fertil Senol
Pays: France
ID NLM: 101693805
Informations de publication
Date de publication:
29 Jan 2024
29 Jan 2024
Historique:
received:
14
08
2023
revised:
18
01
2024
accepted:
21
01
2024
medline:
1
2
2024
pubmed:
1
2
2024
entrez:
31
1
2024
Statut:
aheadofprint
Résumé
To describe pregnancy outcome of kidney transplant patients till 1 year post-partum. This retrospective, monocentric study included 15 kidney transplant patients who presented 18 pregnancy, between January 2000 and January 2020. For each of them, we searched for possible obstetrical, fetal and renal complications and we evaluated renal function before, during and after pregnancy. The live birth rate was 84% (16/19) with an average gestational age at delivery of 37 weeks of gestation. The rate of prematurity was 50% (8/16), gestational diabetes was 16,6% (3/18) and preeclampsia was 27.7% (5/18). Cesarean section was performed in 61,1% (11/18) of cases including, 81.8% (9/11) unplanned surgery. The average birth weight was 2635 grams and 37.5% (6/16) of the newborn were small for gestational age. All patients had stable renal function before conception of pregnancy. We noticed two acute graft rejection during pregnancy with only one resulting in graft loss. 4 patients had a reduced graft function in 12 months of the post-partum. Risk of maternal, fetal and renal complications remained high in kidney transplant recipients. Pregnancy should be carefully planned in transplanted women associated with adequate follow-up according to clinical guidelines (normal renal function and blood pressure without proteinuria before pregnancy, no recent graft rejection, period of one year after transplant respected and no teratogenic treatment in the month before pregnancy).
Identifiants
pubmed: 38296107
pii: S2468-7189(24)00034-5
doi: 10.1016/j.gofs.2024.01.011
pii:
doi:
Types de publication
English Abstract
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Informations de copyright
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