Decarboxylative [3 + 2] cycloaddition of propargyl cyclic carbonates with

The development of efficient and straightforward strategies for obtaining chiral complex molecules from readily available starting materials is of great value in drug discovery. The stereodivergent synthesis of heterocycles bearing quaternary centers remains a challenge due to inherent steric issues. Herein, we report an enantioselective copper-catalyzed decarboxylative [3 + 2] cycloaddition of propargyl cyclic carbonates/carbamates with 4-hydroxycoumarins to afford a wide range of dihydrofuro[3,2-