A non-toxic recombinant protein rSUMO-CPBm4 as a potential vaccine candidate against Clostridium perfringens type C beta enterotoxemia.

Journal

Tropical biomedicine
ISSN: 2521-9855
Titre abrégé: Trop Biomed
Pays: Malaysia
ID NLM: 8507086

Informations de publication

Date de publication:
01 Dec 2023
Historique:
medline: 3 2 2024
pubmed: 3 2 2024
entrez: 3 2 2024
Statut: ppublish

Résumé

Beta toxin (CPB) is a lethal toxin and plays a key role in enterotoxemia of ruminants caused by Clostridium perfringens type C strain. The existing vaccines based on crude CPB need time-consuming detoxification and difficult quality control steps. In this study, we synthesized the rCPB

Identifiants

DOI: 10.47665/tb.40.4.004 PMID: 38308826
pubmed: 38308826
doi: 10.47665/tb.40.4.004
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

400-405

Auteurs

Y Goa (Y)

The Key Sericultural Laboratory of Agricultural Ministry, College of Biotechnology, Southwest University, Chongqing, 400715, PR China.
Chongqing Auleon Biological Co., Ltd., Rongchang, Chongqing, 402460, PR China.

J G Du (JG)

Department of Bacterial Biologics, China Institute of Veterinary Drug Control, No. 8 Zhongguancun South Street, Beijing 100-081, China.

C Jirapattharasate (C)

Department of Pre-Clinic and Applied Animal Science, Faculty of Veterinary Science, Mahidol University, 999 Phutthamonthon Sai4, Salaya, Phutthamonthon, Nakhon Pathom, Thailand, 73170.

E Galon (E)

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.

S W Ji (SW)

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.

Z G Ran (ZG)

Chongqing Auleon Biological Co., Ltd., Rongchang, Chongqing, 402460, PR China.

Y Q Xia (YQ)

The Key Sericultural Laboratory of Agricultural Ministry, College of Biotechnology, Southwest University, Chongqing, 400715, PR China.

Classifications MeSH