Predictive risk model of recurrence of acute diverticulitis after the first episode.


Journal

World journal of surgery
ISSN: 1432-2323
Titre abrégé: World J Surg
Pays: United States
ID NLM: 7704052

Informations de publication

Date de publication:
Feb 2024
Historique:
received: 21 09 2023
accepted: 19 11 2023
medline: 5 2 2024
pubmed: 4 2 2024
entrez: 3 2 2024
Statut: ppublish

Résumé

The recurrence of acute diverticulitis (AD) of the colon is frequent and leads to hospital readmissions and the need for elective surgery in selected cases. It is important to individualize risk factors and develop predictive tools for their identification. This prospective observational study included 368 patients who were diagnosed with AD between 2016 and 2021 in a tertiary general university hospital during their first episode and who had a good response to antibiotic, percutaneous, or peritoneal lavage treatment. Univariate and multivariate Cox regression analyses of the variables associated with recurrence were performed. Subsequently, a predictive risk score was developed and validated through survival studies. After a median follow-up of 50 months, there were 71 (19.3%) cases of recurrence out of a total of 368 patients. The mean time of recurrence was 15 months, and 73.3% of cases of recurrence occurred before 2 years of follow-up. Recurrence was independently associated with presentation with colonic perforation in the antimesenteric location (HR 3.67 95% CI [1.59-8.4]) and a CRP level greater than 100 mg/dl (HR 1.69 95% CI [1.04-2.77). A score with 5 variables was created that differentiated two risk groups: intermediate risk (0-3 points), with 19% recurrence and high risk (more than 3 points), with 42% recurrence. The risk of recurrence after the first episode of diverticulitis can be estimated using predictive scores. The detection of high-risk patients facilitates the individualization of follow-up and treatment.

Identifiants

pubmed: 38310307
doi: 10.1002/wjs.12045
doi:

Types de publication

Observational Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

466-473

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2023 International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).

Références

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Auteurs

Juan Carlos Pastor-Mora (JC)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Carlos Fortea-Sanchís (C)

Department of General and Digestive Surgery, Regional Hospital of Vinaròs, Castellón de la Plana, Castellón, Spain.

Alba Coret-Franco (A)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Juan Antonio García-Martínez (JA)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Rebeca Cosa-Rodriguez (R)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Jesus Nomdédeu-Guinot (J)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Juan Gibert-Gerez (J)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Manuel Laguna-Sastre (M)

Coloproctology Unit, General and Digestive Surgery Department, Castellón General University Hospital, Castellón de la Plana, Spain.

Antoni Llueca (A)

Department of Medicine, Jaume I de Castelló University, Castellón de la Plana, Castellón, Spain.

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