Insight into the molecular interaction between the anticancer drug, enzalutamide and human alpha-2-macroglobulin: Biochemical and biophysical approach.
Alpha-2-macroglobulin
Circular dichroism
Enzalutamide
Fluorescence spectroscopy
Isothermal titration calorimetry
Journal
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
ISSN: 1873-3557
Titre abrégé: Spectrochim Acta A Mol Biomol Spectrosc
Pays: England
ID NLM: 9602533
Informations de publication
Date de publication:
26 Jan 2024
26 Jan 2024
Historique:
received:
19
10
2023
revised:
21
01
2024
accepted:
22
01
2024
medline:
5
2
2024
pubmed:
5
2
2024
entrez:
4
2
2024
Statut:
aheadofprint
Résumé
The drug pharmacokinetics is affected upon binding with proteins, thus making drug-protein interactions crucial. This study investigated the interaction between enzalutamide and human major antiproteinase alpha-2-macroglobulin (α
Identifiants
pubmed: 38310741
pii: S1386-1425(24)00123-9
doi: 10.1016/j.saa.2024.123957
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
123957Informations de copyright
Copyright © 2024 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.