Ribosomal Protein Cluster Organization in Asgard Archaea.

It has been proposed that the superphylum of Asgard Archaea may represent a historical link between the Archaea and Eukarya. Following the discovery of the Archaea, it was soon appreciated that archaeal ribosomes were more similar to those of Eukarya rather than Bacteria. Coupled with other eukaryotic-like features, it has been suggested that the Asgard Archaea may be directly linked to eukaryotes. However, the genomes of Bacteria and non-Asgard Archaea generally organize ribosome-related genes into clusters that likely function as operons. In contrast, eukaryotes typically do not employ an operon strategy. To gain further insight into conservation of the r-protein genes, the genome order of conserved ribosomal protein (r-protein) coding genes was identified in 17 Asgard genomes (thirteen complete genomes and four genomes with less than 20 contigs) and compared with those found previously in non-Asgard archaeal and bacterial genomes. A universal core of two clusters of 14 and 4 cooccurring r-proteins, respectively, was identified in both the Asgard and non-Asgard Archaea. The equivalent genes in the

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Copyright © 2023 Madhan R. Tirumalai et al.

Déclaration de conflit d'intérêts

All authors declare they have no competing interests. LAK and ELS were student volunteers on this work. LAK was a fresh graduate from Clements High School, and ELS had just completed his 10th grade at Obra D. Tompkins High School, who volunteered with the group of Dr. George E. Fox at the University of Houston.