Technical note: Errors introduced when using Dose Voxel Kernels for estimating absorbed dose from radiopharmaceutical therapies involving alpha emitters.
Monte Carlo methods
cell-scale dosimetry
dose voxel kernel
radiopharmaceutical therapy
stochastic distribution
Journal
Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746
Informations de publication
Date de publication:
05 Feb 2024
05 Feb 2024
Historique:
revised:
20
12
2023
received:
17
08
2023
accepted:
16
01
2024
medline:
5
2
2024
pubmed:
5
2
2024
entrez:
5
2
2024
Statut:
aheadofprint
Résumé
In radiopharmaceutical therapies (RPT) involving beta emitters, absorbed dose (D This work aims at illustrating how use of DVKs affect the resulting D To illustrate the issues associated with DVK for alpha radiopharmaceutical therapies at the microscale, a tumor cluster model was used to compare beta ( For beta-emitter ( Our results demonstrate that the use of DVK methods for alpha emitters can lead to an overestimation in the calculated D
Sections du résumé
BACKGROUND
BACKGROUND
In radiopharmaceutical therapies (RPT) involving beta emitters, absorbed dose (D
PURPOSE
OBJECTIVE
This work aims at illustrating how use of DVKs affect the resulting D
METHODS
METHODS
To illustrate the issues associated with DVK for alpha radiopharmaceutical therapies at the microscale, a tumor cluster model was used to compare beta (
RESULTS
RESULTS
For beta-emitter (
CONCLUSIONS
CONCLUSIONS
Our results demonstrate that the use of DVK methods for alpha emitters can lead to an overestimation in the calculated D
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIH HHS
ID : R01 CA235741
Pays : United States
Informations de copyright
© 2024 American Association of Physicists in Medicine.
Références
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