Production and Purification of Plasmodium Circumsporozoite Protein in Lactococcus lactis.

Circumsporozoite protein (CSP) Cloning Lactococcus lactis Plasmodium falciparum Purification Recombinant protein expression malaria

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2024
Historique:
medline: 5 2 2024
pubmed: 5 2 2024
entrez: 5 2 2024
Statut: ppublish

Résumé

Malaria is a vector-borne disease caused by Plasmodium parasites of which Plasmodium falciparum contributed to an estimated 247 million cases worldwide in 2021 (WHO malaria report 2022). The P. falciparum Circumsporozoite protein (PfCSP) covers the surface of the sporozoite which is critical to cell invasion in the human host. PfCSP is the leading pre-erythrocytic vaccine candidate and forms the basis of the RTS'S (Mosquirix

Identifiants

pubmed: 38315362
doi: 10.1007/978-1-0716-3666-4_7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109-121

Informations de copyright

© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Références

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Auteurs

Mohammad Naghizadeh (M)

Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Centre for Medical Parasitology at Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

Susheel K Singh (SK)

Biotherapeutic and Vaccine Research Division, ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India.

Jordan Plieskatt (J)

Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.

Ebenezer Addo Ofori (EA)

Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Centre for Medical Parasitology at Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

Michael Theisen (M)

Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Centre for Medical Parasitology at Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

Classifications MeSH