Patient Reported Quality of Recovery after Sedation for Endoscopy in the Elderly.

Although sedation is critical in minimizing discomforts in patients, conflicting data regarding the safety of sedation among the elderly population exist. This prospective study aimed to compare the quality of recovery (QoR) from gastrointestinal endoscopy performed under sedation between elderly and younger patients. We included 177 patients aged 40-64 (group 1, n = 66), 65-79 (group 2, n = 76), and ≥80 (group 3, n = 35) years. QoR was assessed one day after the procedure using the QoR 15 (QoR-15) questionnaire, which is a 15-item questionnaire with scores ranging from 0-150. Patient demographic, procedural, and sedation data were collected, and neurocognitive function was assessed before and a day after sedation. Groups 1 and 3 differed according to the Mini-Cog test, and 3-word memory test performed before and the procedure (p < 0.001). QoR-15 scores between groups were not different (139 ± 19 group 1, 141 ± 17 group 2, and 147 ± 26 group 3; p > 0.05). Patients in groups 3 and 2 were administered lower doses of propofol and midazolam than those in group 1. The incidence of hypoxemia (SaO2 <90% for >60 s) was lower in groups 1 and 2 than in group 3 (p = 0.01). As indicated by the QoR-15 questionnaire, the quality of recovery from sedation was not significantly different between the study groups.

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The Author(s). Published by S. Karger AG, Basel.