Bystander activated CD8


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
05 Feb 2024
Historique:
received: 09 02 2022
accepted: 21 12 2023
medline: 6 2 2024
pubmed: 6 2 2024
entrez: 5 2 2024
Statut: epublish

Résumé

Although many viral infections are linked to the development of neurological disorders, the mechanism governing virus-induced neuropathology remains poorly understood, particularly when the virus is not directly neuropathic. Using a mouse model of Zika virus (ZIKV) infection, we found that the severity of neurological disease did not correlate with brain ZIKV titers, but rather with infiltration of bystander activated NKG2D

Identifiants

pubmed: 38316762
doi: 10.1038/s41467-023-44667-0
pii: 10.1038/s41467-023-44667-0
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

896

Informations de copyright

© 2024. The Author(s).

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Auteurs

Elizabeth Balint (E)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Emily Feng (E)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Elizabeth C Giles (EC)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Tyrah M Ritchie (TM)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Alexander S Qian (AS)

Thrombosis and Atherosclerosis Research Institute, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton Health Sciences, Hamilton, ON, Canada.

Fatemeh Vahedi (F)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Amelia Montemarano (A)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Ana L Portillo (AL)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Jonathan K Monteiro (JK)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Bernardo L Trigatti (BL)

Thrombosis and Atherosclerosis Research Institute, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton Health Sciences, Hamilton, ON, Canada.

Ali A Ashkar (AA)

McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada. ashkara@mcmaster.ca.

Classifications MeSH