Strategies to combine 3D vasculature and brain CTA with deep neural networks: Application to LVO.

Machine learning Medical imaging Neural networks Neuroanatomy

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
16 Feb 2024
Historique:
received: 13 11 2023
revised: 19 12 2023
accepted: 08 01 2024
medline: 6 2 2024
pubmed: 6 2 2024
entrez: 6 2 2024
Statut: epublish

Résumé

Automated tools to detect large vessel occlusion (LVO) in acute ischemic stroke patients using brain computed tomography angiography (CTA) have been shown to reduce the time for treatment, leading to better clinical outcomes. There is a lot of information in a single CTA and deep learning models do not have an obvious way of being conditioned on areas most relevant for LVO detection, i.e., the vasculature structure. In this work, we compare and contrast strategies to make convolutional neural networks focus on the vasculature without discarding context information of the brain parenchyma and propose an attention-inspired strategy to encourage this. We use brain CTAs from which we obtain 3D vasculature images. Then, we compare ways of combining the vasculature and the CTA images using a general-purpose network trained to detect LVO. The results show that the proposed strategies allow to improve LVO detection and could potentially help to learn other cerebrovascular-related tasks.

Identifiants

pubmed: 38318348
doi: 10.1016/j.isci.2024.108881
pii: S2589-0042(24)00102-0
pmc: PMC10838777
doi:

Types de publication

Journal Article

Langues

eng

Pagination

108881

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

Auteurs

Uma M Lal-Trehan Estrada (UM)

Research institute of Computer Vision and Robotics, University of Girona, Girona, Spain.

Arnau Oliver (A)

Research institute of Computer Vision and Robotics, University of Girona, Girona, Spain.

Sunil A Sheth (SA)

McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.

Xavier Lladó (X)

Research institute of Computer Vision and Robotics, University of Girona, Girona, Spain.

Luca Giancardo (L)

Center for Precision Health, McWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, USA.

Classifications MeSH