Overall Survival and Response with Nivolumab and Relatlimab in Advanced Melanoma.


Journal

NEJM evidence
ISSN: 2766-5526
Titre abrégé: NEJM Evid
Pays: United States
ID NLM: 9918317485806676

Informations de publication

Date de publication:
Apr 2023
Historique:
medline: 6 2 2024
pubmed: 6 2 2024
entrez: 6 2 2024
Statut: ppublish

Résumé

Survival and Response with Nivolumab and RelatlimabIn this follow-up, patients with unresectable stage III or IV melanoma were randomly assigned to receive nivolumab + relatlimab or nivolumab alone. After approximately 6 months of additional follow-up, the combination's median progression-free survival was 10.2 months versus 4.6 months for monotherapy. The difference in overall survival rates was not statistically significant.

Identifiants

pubmed: 38320023
doi: 10.1056/EVIDoa2200239
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

EVIDoa2200239

Commentaires et corrections

Type : ErratumIn

Auteurs

Georgina V Long (GV)

Melanoma Institute Australia, The University of Sydney, Royal North Shore and Mater Hospitals, Sydney.

F Stephen Hodi (F)

Dana-Farber Cancer Institute, Boston.

Evan J Lipson (EJ)

Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore.

Dirk Schadendorf (D)

Department of Dermatology, University Hospital Essen, Essen, Germany.
German Cancer Consortium, Partner Site Essen, Essen, Germany.

Paolo A Ascierto (PA)

Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale," Naples, Italy.

Luis Matamala (L)

Department of Oncology, Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.

Pamela Salman (P)

Department of Oncology, Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.

Erika Castillo Gutiérrez (E)

FAICIC Clinical Research, Veracruz, Mexico.

Piotr Rutkowski (P)

Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland.

Helen J Gogas (HJ)

Department of Medicine, National and Kapodistrian University of Athens, Athens.

Christopher D Lao (CD)

Michigan Medicine, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.

Juliana Janoski De Menezes (J)

Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil.

Stéphane Dalle (S)

Unit of Dermatology, Hospices Civils de Lyon, Cancer Research Center of Lyon, Pierre-Bénite, France.

Ana Arance (A)

Department of Medical Oncology, Hospital Clinic Barcelona and IDIBAPS, Barcelona.

Jean-Jacques Grob (JJ)

Aix-Marseille University, CHU Timone, Marseille, France.

Sarah Keidel (S)

Bristol Myers Squibb, Princeton, New Jersey.

Anadil Shaikh (A)

Bristol Myers Squibb, Princeton, New Jersey.

Anne Marie Sobiesk (AM)

Bristol Myers Squibb, Princeton, New Jersey.

Sonia Dolfi (S)

Bristol Myers Squibb, Princeton, New Jersey.

Hussein A Tawbi (HA)

Department of Melanoma Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston.

Classifications MeSH