Alleviation of monocyte exhaustion by BCG derivative mycolic acid.
Epigenetics
Immunology
Molecular biology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
16 Feb 2024
16 Feb 2024
Historique:
received:
15
09
2023
revised:
27
11
2023
accepted:
16
01
2024
medline:
7
2
2024
pubmed:
7
2
2024
entrez:
7
2
2024
Statut:
epublish
Résumé
Monocyte exhaustion with sustained pathogenic inflammation and immune-suppression, a hallmark of sepsis resulting from systemic infections, presents a challenge with limited therapeutic solutions. This study identified Methoxy-Mycolic Acid (M-MA), a branched mycolic acid derived from
Identifiants
pubmed: 38323001
doi: 10.1016/j.isci.2024.108978
pii: S2589-0042(24)00199-8
pmc: PMC10845070
doi:
Types de publication
Journal Article
Langues
eng
Pagination
108978Informations de copyright
© 2024 The Author(s).
Déclaration de conflit d'intérêts
The authors declare no competing interests.