Type 2-polarized memory B cells hold allergen-specific IgE memory.

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
07 Feb 2024
Historique:
medline: 7 2 2024
pubmed: 7 2 2024
entrez: 7 2 2024
Statut: ppublish

Résumé

Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by regenerating IgE-producing plasma cells upon allergen encounter. Here, we report a population of type 2-polarized MBCs defined as CD23

Identifiants

DOI: 10.1126/scitranslmed.adi0944 PMID: 38324637
pubmed: 38324637
doi: 10.1126/scitranslmed.adi0944
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadi0944

Auteurs

Joshua F E Koenig (JFE)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0000-0002-8909-5039

Niels Peter H Knudsen (NPH)

ALK-Abelló A/S, 2970 Hørsholm, Denmark.
ORCID: 0000-0003-1400-5657

Allyssa Phelps (A)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0000-0002-5025-7459

Kelly Bruton (K)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0000-0003-0817-6134

Ilka Hoof (I)

ALK-Abelló A/S, 2970 Hørsholm, Denmark.

Gitte Lund (G)

ALK-Abelló A/S, 2970 Hørsholm, Denmark.
ORCID: 0000-0003-2221-7465

Danielle Della Libera (DD)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0009-0000-3633-051X

Anders Lund (A)

ALK-Abelló A/S, 2970 Hørsholm, Denmark.
ORCID: 0000-0003-0051-8400

Lars Harder Christensen (LH)

ALK-Abelló A/S, 2970 Hørsholm, Denmark.
ORCID: 0000-0003-4230-7820

David R Glass (DR)

Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
ORCID: 0000-0001-9924-167X

Tina D Walker (TD)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.

Allison Fang (A)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0000-0002-5865-8695

Susan Waserman (S)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0000-0002-2136-5995

Manel Jordana (M)

Schroeder Allergy and Immunology Research Institute, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
ORCID: 0000-0002-5861-5994

Peter S Andersen (PS)

ALK-Abelló A/S, 2970 Hørsholm, Denmark.
ORCID: 0000-0001-7615-8224

Classifications MeSH