The Mutographs biorepository: A unique genomic resource to study cancer around the world.

Humans Neoplasms / diagnosis Genomics Databases, Factual Delivery of Health Care Biological Specimen Banks

Journal

Cell genomics
ISSN: 2666-979X
Titre abrégé: Cell Genom
Pays: United States
ID NLM: 9918284260106676

Informations de publication

Date de publication:
13 Mar 2024
Historique:
received: 17 07 2023
revised: 24 10 2023
accepted: 10 01 2024
medline: 18 3 2024
pubmed: 8 2 2024
entrez: 7 2 2024
Statut: ppublish

Résumé

Large-scale biorepositories and databases are essential to generate equitable, effective, and sustainable advances in cancer prevention, early detection, cancer therapy, cancer care, and surveillance. The Mutographs project has created a large genomic dataset and biorepository of over 7,800 cancer cases from 30 countries across five continents with extensive demographic, lifestyle, environmental, and clinical information. Whole-genome sequencing is being finalized for over 4,000 cases, with the primary goal of understanding the causes of cancer at eight anatomic sites. Genomic, exposure, and clinical data will be publicly available through the International Cancer Genome Consortium Accelerating Research in Genomic Oncology platform. The Mutographs sample and metadata biorepository constitutes a legacy resource for new projects and collaborations aiming to increase our current research efforts in cancer genomic epidemiology globally.

Identifiants

DOI: 10.1016/j.xgen.2024.100500 PMID: 38325367 PMC: PMC10943582
pubmed: 38325367
pii: S2666-979X(24)00027-2
doi: 10.1016/j.xgen.2024.100500
pmc: PMC10943582
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

100500

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of interests M.R.S. is founder of, consultant to, and stockholder in Quotient Therapeutics. L.B.A. is a compensated consultant and has equity interest in io9, LLC, and Genome Insight. His spouse is an employee of Biotheranostics, Inc. L.B.A. is also an inventor of a US patent 10,776,718 for source identification by non-negative matrix factorization. L.B.A. declares US provisional applications with serial numbers 63/289,601; 63/269,033; and 63/483,237. L.B.A. also declares US provisional applications with serial numbers 63/366,392; 63/367,846; 63/412,835; and 63/492,348.

Références

J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Annu Rev Pathol. 2019 Jan 24;14:83-103
pubmed: 30125150
Br J Anaesth. 2023 Mar;130(3):e401-e403
pubmed: 36682937
Nat Rev Cancer. 2021 Apr;21(4):239-256
pubmed: 33627798
Nature. 2001 May 17;411(6835):390-5
pubmed: 11357148
Lancet. 2016 Jun 11;387(10036):2367-8
pubmed: 27312293
Nat Rev Cancer. 2021 Oct;21(10):619-637
pubmed: 34316057
Gut. 2023 May;72(5):846-854
pubmed: 36241389
Nat Genet. 2020 Nov;52(11):1139-1143
pubmed: 33106632
Cancer Cell. 2021 Feb 8;39(2):125-129
pubmed: 33220180
Nat Genet. 2021 Nov;53(11):1553-1563
pubmed: 34663923
Lancet Oncol. 2009 Jan;10(1):13-4
pubmed: 19115512
Science. 2022 Apr 22;376(6591):
pubmed: 35949260
JAMA Netw Open. 2018 Dec 7;1(8):e185937
pubmed: 30646298
Cancer Epidemiol. 2011 Aug;35(4):309-19
pubmed: 21470937
JCO Glob Oncol. 2020 Mar;6:486-499
pubmed: 32213095
J Natl Cancer Inst. 2021 May 4;113(5):580-587
pubmed: 32944748
Gastroenterology. 2022 Sep;163(3):649-658.e2
pubmed: 35671803
Int J Epidemiol. 2022 Aug 10;51(4):1317-1327
pubmed: 35312764
N Engl J Med. 2021 May 27;384(21):2039-2052
pubmed: 34042390
Cancer Causes Control. 2010 Dec;21(12):2213-21
pubmed: 20835759
Science. 1995 Jul 14;269(5221):164-9
pubmed: 7618077
Eur J Cancer. 2011 Sep;47(13):1928-37
pubmed: 21458985
J Natl Cancer Inst. 2022 Mar 8;114(3):353-360
pubmed: 34743211
Gastroenterology. 2019 Apr;156(5):1416-1427
pubmed: 30611753
Int J Cancer. 2002 Nov 20;102(3):271-4
pubmed: 12397650
Lancet Oncol. 2023 Nov;24(11):1206-1218
pubmed: 37837979
IARC Sci Publ. 1993;(123):1-10
pubmed: 8365761
Gastroenterology. 2018 Jan;154(2):360-373
pubmed: 28823862
Nature. 2020 Feb;578(7793):82-93
pubmed: 32025007
Jpn J Clin Oncol. 2007 Jan;37(1):74-5
pubmed: 17272323
Sci Adv. 2022 Jun 10;8(23):eabn3328
pubmed: 35675391
Nature. 2019 Nov;575(7781):210-216
pubmed: 31645765
Nature. 2023 Apr;616(7955):159-167
pubmed: 37020004
Lancet Reg Health Am. 2022 Sep;13:None
pubmed: 36189115
Nature. 2019 Jun;570(7762):514-518
pubmed: 31217584
Int J Epidemiol. 2022 Jun 13;51(3):830-838
pubmed: 35244716
Gastroenterology. 2020 Jul;159(1):335-349.e15
pubmed: 32247694
Lancet Oncol. 2020 Nov;21(11):1407-1408
pubmed: 33038940
JAMA Oncol. 2016 Aug 01;2(8):1070-4
pubmed: 27366979
Nat Rev Cancer. 2022 Oct;22(10):576-591
pubmed: 35854147
Nature. 2021 Oct;598(7881):510-514
pubmed: 34646013
Lancet Oncol. 2021 Aug;22(8):1071-1080
pubmed: 34270924
Eur Urol. 2015 Mar;67(3):519-30
pubmed: 25449206
Environ Int. 2021 Jul;152:106485
pubmed: 33689906
Genome Res. 2009 Sep;19(9):1655-64
pubmed: 19648217
Lancet Oncol. 2015 Dec;16(16):1599-600
pubmed: 26514947
Lancet Oncol. 2021 Dec;22(12):1661-1662
pubmed: 34774220
Nat Commun. 2014 Oct 29;5:5135
pubmed: 25351205
Nat Med. 2022 Feb;28(2):243-250
pubmed: 35145307
Am J Epidemiol. 2008 Feb 15;167(4):438-46
pubmed: 18048375
Lancet Oncol. 2015 Jan;16(1):36-46
pubmed: 25467404

Auteurs

Sandra Perdomo (S)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Behnoush Abedi-Ardekani (B)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Ana Carolina de Carvalho (AC)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Aida Ferreiro-Iglesias (A)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Valérie Gaborieau (V)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Thomas Cattiaux (T)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Hélène Renard (H)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Priscilia Chopard (P)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Christine Carreira (C)

Evidence Synthesis and Classification Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Andreea Spanu (A)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Arash Nikmanesh (A)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Ricardo Cortez Cardoso Penha (RC)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Samuel O Antwi (SO)

Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.

Patricia Ashton-Prolla (P)

Experimental Research Center, Genomic Medicine Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; Post-Graduate Program in Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Cristina Canova (C)

Unit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Padova, Italy.

Taned Chitapanarux (T)

Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.

Riley Cox (R)

Ontario Tumour Bank, Ontario Institute for Cancer Research, Toronto, ON, Canada.

Maria Paula Curado (MP)

Department of Epidemiology, A.C. Camargo Cancer Center, São Paulo, Brazil.

José Carlos de Oliveira (JC)

Associação de Combate ao Câncer em Goiás Hospital Araújo Jorge Goiânia, Goiânia, Brazil.

Charles Dzamalala (C)

University of Malawi College of Medicine, Blantyre, Malawi.

Elenora Fabianova (E)

Regional Authority of Public Health, Banská Bystrica, Slovakia.

Lorenzo Ferri (L)

Departments of Surgery and Oncology, McGill University, Montreal, QC, Canada.

Rebecca Fitzgerald (R)

Early Cancer Institute, University of Cambridge, Cambridge, UK.

Lenka Foretova (L)

Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic.

Steven Gallinger (S)

Mount Sinai Hospital; Ontario Institute for Cancer Research (OICR), Toronto, ON, Canada.

Alisa M Goldstein (AM)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.

Ivana Holcatova (I)

Institute of Public Health & Preventive Medicine, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic; Department of Oncology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

Antonio Huertas (A)

National Cancer Institute, Bogotá, Colombia.

Vladimir Janout (V)

Faculty of Health Sciences, Palacky University, Olomouc, Czech Republic.

Sonata Jarmalaite (S)

Laboratory of Genetic Diagnostic, National Cancer Institute, Vilnius, Lithuania; Department of Botany and Genetics, Institute of Biosciences, Vilnius University, Vilnius, Lithuania.

Radka Kaneva (R)

Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.

Luiz Paulo Kowalski (LP)

Department of Epidemiology, A.C. Camargo Cancer Center, São Paulo, Brazil; University of São Paulo Medical School, São Paulo, Brazil.

Tomislav Kulis (T)

Department of Urology, University Hospital Center Zagreb, Zagreb, Croatia; University of Zagreb School of Medicine, Zagreb, Croatia.

Pagona Lagiou (P)

National and Kapodistrian University of Athens, Athens, Greece.

Jolanta Lissowska (J)

The Maria Sklodowska-Cure National Research Institute of Oncology, Warsaw, Poland.

Reza Malekzadeh (R)

Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Dana Mates (D)

Occupational Health and Toxicology, National Center for Environmental Risk Monitoring, National Institute of Public Health, Bucharest, Romania.

Valerie McCorrmack (V)

Environment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.

Diana Menya (D)

Moi University, School of Public Health, Eldoret, Kenya.

Sharayu Mhatre (S)

Division of Molecular Epidemiology and Population Genomics, Centre for Cancer Epidemiology, Tata Memorial Centre, Mumbai, India.

Blandina Theophil Mmbaga (BT)

Department of Surgery, Santa Casa School of Medicine, São Paulo, Brazil.

André de Moricz (A)

Kilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre & Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Péter Nyirády (P)

Semmelweis University, Budapest, Hungary.

Miodrag Ognjanovic (M)

IOCPR- International Organization for Cancer Prevention and Research, Serbia, Belgrade.

Kyriaki Papadopoulou (K)

Hellenic Cooperative Oncology Group (HeCOG), Athens, Greece.

Jerry Polesel (J)

Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.

Mark P Purdue (MP)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

Stefan Rascu (S)

Urology Department, "Carol Davila" University of Medicine and Pharmacy - "Prof. Dr. Th. Burghele" Clinical Hospital, Bucharest, Romania.

Lidia Maria Rebolho Batista (LM)

Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.

Rui Manuel Reis (RM)

Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil; Life and Health Sciences Research Institute (ICVS), School of Medicine, Minho University, Braga, Portugal.

Luis Felipe Ribeiro Pinto (LF)

Brazilian National Cancer Institute, Rio de Janeiro, Brazil.

Paula A Rodríguez-Urrego (PA)

Pathology Department, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia.

Surasak Sangkhathat (S)

Translational Medicine Research Center, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.

Suleeporn Sangrajrang (S)

National Cancer Institute, Bangkok, Thailand.

Tatsuhiro Shibata (T)

Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan; Division of Cancer Genomics, National Cancer Center Research Institute, Chuo-ku, Japan.

Eduard Stakhovsky (E)

National Cancer Institute, Kiev, Ukraine.

Beata Świątkowska (B)

Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland.

Carlos Vaccaro (C)

Instituto Medicina Traslacional e Ingenieria Biomedica - CONICET, Buenos Aires, Argentina.

Jose Roberto Vasconcelos de Podesta (JR)

Hospital Santa Rita AFECC - Associação Feminina de Educação e Combate ao Câncer, Vitoria, Brazil.

Naveen S Vasudev (NS)

Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.

Marta Vilensky (M)

Instituto de Oncología Angel Roffo, Universidad de Buenos Aires, Buenos Aires, Argentina.

Jonathan Yeung (J)

University Health Network, Toronto, ON, Canada.

David Zaridze (D)

Clinical Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia.

Kazem Zendehdel (K)

Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.

Ghislaine Scelo (G)

Observational & Pragmatic Research Institute Pte., Ltd., Singapore, Singapore.

Estelle Chanudet (E)

Department of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands.

Jingwei Wang (J)

Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.

Stephen Fitzgerald (S)

Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.

Calli Latimer (C)

Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.

Sarah Moody (S)

Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.

Laura Humphreys (L)

Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.

Ludmil B Alexandrov (LB)

Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.

Michael R Stratton (MR)

Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute, Cambridge, UK.

Paul Brennan (P)

Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France. Electronic address: brennanp@iarc.who.int.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Mutographs biorepository: A unique genomic...
questionsmedicales.fr › Tumeurs › The Mutographs biorepository: A unique genomic...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › The Mutographs biorepository: A unique genomic...
questionsmedicales.fr › Sciences de l'information › Mémorisation et recherche des informations › Bases de données comme sujet › Bases de données factuelles › The Mutographs biorepository: A unique genomic...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Prestations des soins de santé › The Mutographs biorepository: A unique genomic...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Établissements de santé › Biobanques › The Mutographs biorepository: A unique genomic...