Mitochondrial deoxyguanosine kinase is required for female fertility in mice.

DGUOK infertility mitochondria nucleoside salvage pathway oocyte maturation

Journal

Acta biochimica et biophysica Sinica
ISSN: 1745-7270
Titre abrégé: Acta Biochim Biophys Sin (Shanghai)
Pays: China
ID NLM: 101206716

Informations de publication

Date de publication:
07 Feb 2024
Historique:
medline: 8 2 2024
pubmed: 8 2 2024
entrez: 8 2 2024
Statut: aheadofprint

Résumé

Mitochondrial homeostasis plays a pivotal role in oocyte maturation and embryonic development. Deoxyguanosine kinase (DGUOK) is a nucleoside kinase that salvages purine nucleosides in mitochondria and is critical for mitochondrial DNA replication and homeostasis in non-proliferating cells.

Identifiants

pubmed: 38327186
doi: 10.3724/abbs.2024003
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Yake Gao (Y)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Rui Dong (R)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Jiacong Yan (J)

Department of Reproductive Medicine, the First People's Hospital of Yunnan Province, Kunming, 650100, China; NHC Key Laboratory of Preconception Health Birth in Western China.

Huicheng Chen (H)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Lei Sang (L)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Xinyi Yao (X)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Die Fan (D)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Xin Wang (X)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Xiaoyuan Zuo (X)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Xu Zhang (X)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Shengyu Yang (S)

Department of Cellular and Molecular Physiology, The Penn State University College of Medicine, Hershey, PA 17033, USA.

Ze Wu (Z)

Department of Reproductive Medicine, the First People's Hospital of Yunnan Province, Kunming, 650100, China; NHC Key Laboratory of Preconception Health Birth in Western China.

Jianwei Sun (J)

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China.

Classifications MeSH